Results 221 to 230 of about 600,274 (298)

Co-infection of Mycobacterium tuberculosis complex and carbapenem-resistant hypervirulent Klebsiella pneumoniae in captive Asiatic black bears: a case report. [PDF]

BMC Vet Res
Leng H, Li W, Xing S, Wu Y, Li H, Sun F, Feng Y, Zhang Y.   +7 more
europepmc   +1 more source

Entretien B1

Romans du hasard, 2020
openaire   +2 more sources

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

Advanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu, Haixin Wang, Qin Shentu, Liang Yuan, Jiangshan Tie, Li Li, Rui Ai, Bochen Ma, Lubin Qi, Yifei Jiang, Xiaohong Fang   +10 more
wiley   +1 more source

Toddlers expect ingroup loyalty to override personal preferences when outgroups are present. [PDF]

Proc Natl Acad Sci U S A
Bian L, Baillargeon R.
europepmc   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Designing B₁-Selective Pulses by Frequency Modulating in a Second Rotating Frame. [PDF]

Magn Reson Med
Kantesaria S, Torres E, Mustafa MM, Idiyatullin D, Ponticorvo S, Adriany G, Michaeli S, Garwood M.   +7 more
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Mechanistic Studies of the Calcium-Dependent Antibiotics via Cofactor Engineering. [PDF]

J Nat Prod
Chiou SL, Chang YC, Chen YR, Ma T, Chu J.   +4 more
europepmc   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source