Results 231 to 240 of about 600,274 (298)

Cerebellar tonic inhibition orchestrates the maturation of information processing and motor coordination. [PDF]

Exp Mol Med
Kwon J, Kim S, Woo J, Tanaka-Yamamoto K, James O, De Schutter E, Hong S, Lee CJ.   +7 more
europepmc   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

HSP90AB1‐Mediated Ubiquitin‐Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress‐Induced Autophagy

Advanced Science, EarlyView.
This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang, Zixuan Guo, Chengwei Cao, Ziying Wang, Zifu Huang, Xiujuan Zhang, Yushu Zheng, Diankun She, Hao Zhu, Lingfeng Yu, Xuelin Zhao, Dongquan Xiang, Song Liao, Xin He, Xintong Ji, Chengsheng Wu, Cheng‐Xiong Xu, Meng Xu   +17 more
wiley   +1 more source

Genomic, Functional, and Evolutionary Insights into a Novel T7-like Phage B1 Infecting Multidrug-Resistant <i>Enterobacter cloacae</i>. [PDF]

Int J Mol Sci
Tsai YC, Teh SH, Huang P, Lin LC, Lin NT.   +4 more
europepmc   +1 more source

A Coupled Multimodal Planar Transmit RF Array for Ultrahigh Field Spine MR Imaging. [PDF]

IEEE Trans Biomed Eng
Zhao Y, Payne K, Ying L, Zhang X.
europepmc   +1 more source

Circular Economy Transition in an Emerging Economy: Current Status and Priorities in Peru. [PDF]

Circ Econ Sustain
Gallego-Schmid A, Rebolledo-Leiva R, Vásquez-Ibarra L, Elorrieta-Mendoza A, Cotohuanca DMP, Henninger CE, Guerrero AB.   +6 more
europepmc   +1 more source

Estimating V̇O₂ max in healthy subjects without maximal effort: a novel protocol using ballistocardiography. [PDF]

Front Sports Act Living
Hossein A, Rabineau J, Questel P, Kobbai A, Migeotte PF, Tordeur C, Balali P, Abdessater E, Gillet A, Haut B, van de Borne P, Faoro V.   +11 more
europepmc   +1 more source

Human class B1 GPCR modulation by plasma membrane lipids. [PDF]

Commun Biol
Chao KW, Wong L, Oqua AI, Kalayan J, Manchanda Y, Gebbie-Rayet J, Hedger G, Tomas A, Rouse SL.   +8 more
europepmc   +1 more source

Decyl caffeate inhibits the proliferation of human triple negative breast cancer cells. [PDF]

Biomedicine (Taipei)
Chao CY, Shyu WC, Lin CL, Chiang EI, Kuo YH, Tang FY.   +5 more
europepmc   +1 more source