Results 191 to 200 of about 31,156,887 (403)

Immunofluorescent Studies on the Inhibition of Influenza A and B Viruses in Mammalian Cell Cultures by Amines and Ammonium Compounds

, 1968
John Oxford, G. C. Schild
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Thermal studies of the rates of the reactions of carbon dioxide in concentrated haemoglobin solutions and in red blood cells. A. The reactions catalysed by carbonic anhydrase. B. The carbamino reactions of oxygenated and deoxygenated haemoglobin

, 1968
John C. Kernohan, F. J. W. Roughton
openalex   +1 more source

Nature of Escherichia coli B(P1) Yielder Cells at the Time of Infection with Restricted T1 [PDF]

, 1969
Laura Winstead, Henry Drexler
openalex   +1 more source

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.

Journal of Clinical Investigation, 2016
C. Turtle, L. Hanafi, C. Berger, T. Gooley, S. Cherian, M. Hudecek, D. Sommermeyer, Katherine Melville, B. Pender, Tanya M Budiarto, E. Robinson, Natalia N Steevens, Colette N. Chaney, L. Soma, Xueyan Chen, C. Yeung, B. Wood, Daniel H. Li, Jianhong Cao, S. Heimfeld, M. Jensen, S. Riddell, D. Maloney   +22 more
semanticscholar   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Chemical Effects of A- and B-Decomposing Enzymes on Blood Group Substances from Red Cells

, 1963
Kei-Ichi Fujisawa, Ken Furukawa, Shoei ISEKI   +2 more
openalex   +2 more sources

Discussion: “Performance of Silicon Solar Cells at High Levels of Solar Radiation” (Pfeiffer, C., Schoffer, P., Spars, B. G., and Duffie, J. A., 1962, ASME J. Eng. Power, 84, pp. 33–38) [PDF]

, 1962
R. B. Gillette, R. J. Tallent
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source