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The International Journal of Biochemistry & Cell Biology, 2005
B cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The fact that humans express a very large repertoire of antibodies is due to the complex mechanism of V(D)J recombination of immunoglobulin (Ig) genes as well as other ...
Juha, Ollila, Mauno, Vihinen
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B cells are an important component of adaptive immunity. They produce and secrete millions of different antibody molecules, each of which recognizes a different (foreign) antigen. The fact that humans express a very large repertoire of antibodies is due to the complex mechanism of V(D)J recombination of immunoglobulin (Ig) genes as well as other ...
Juha, Ollila, Mauno, Vihinen
openaire +4 more sources
B Cell Activation and B Cell Tolerance
Autoimmune Diseases, 2014Kristine Oleinika +2 more
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CD5 B cells and B-cell malignancies
Current Opinion in Hematology, 1999Over the past year, progress has been made in understanding of the physiology and disease associations of CD5+ (B1) B cells, although their exact role in pathogenesis remains unclear. Earlier studies on the negative function of CD5 within the B-cell receptor complex have been substantiated, and it seems likely that soon the signaling pathways used by ...
Andrew P. Jewell +3 more
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Lupus, 2002
This session had as its central theme the analysis of peptide epitopes and their relationship with lupus pathogenesis. New information on the role of peptides opens up the possibility of treatments based on inducing immunological tolerance although care needs to be taken since it is diffi cult to predict flare or remission of disease after exposure to
Michael R. Ehrenstein, Bevra H. Hahn
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This session had as its central theme the analysis of peptide epitopes and their relationship with lupus pathogenesis. New information on the role of peptides opens up the possibility of treatments based on inducing immunological tolerance although care needs to be taken since it is diffi cult to predict flare or remission of disease after exposure to
Michael R. Ehrenstein, Bevra H. Hahn
openaire +2 more sources