Results 231 to 238 of about 288,045 (238)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Loss of ovarian function and estrogen therapy remodel the brain's synaptic and metabolic proteome. [PDF]

Am J Physiol Regul Integr Comp Physiol
Salathe SF, Franczak E, Busick Z, Boakye FB, Allen J, Lutkewitte A, Wilkins H, Thyfault J, Kugler BA.   +8 more
europepmc   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

TDTAC: a generalized time-dependent torsion angle correlation framework for resolving directional coordination in large biomolecular assemblies. [PDF]

Front Mol Biosci
Escobar Palacio C, Shen T, Chang CA.
europepmc   +1 more source

Development of an indirect ELISA for the detection of venezuelan equine encephalitis virus specific antibodies in horses. [PDF]

PLoS One
Chevrier M, Mathews-Martin L, Mariteragi-Helle T, Dumarest M, Boudjadi Y, Bréard E, Turpaud M, Deshayes T, Vissani MA, Vinueza RL, Coello Peralta R, Vanhomwegen J, Zientara S, Beck C, Martin-Latil S, Desprès P, Gonzalez G, Migné CV.   +17 more
europepmc   +1 more source

Electrostatic Interaction as a Key Modulator of Na⁺,K⁺-ATPase Function. [PDF]

J Membr Biol
Fairuz S, Li Z, Gorman A, Cornelius F, Clarke RJ.   +4 more
europepmc   +1 more source

Diol-enhanced natural deep eutectic solvents for efficient poplar pretreatment. [PDF]

Front Chem
Yoon C, Ryu J, Jeong S, Eudes A, Kim KH, Yoo CG.   +5 more
europepmc   +1 more source

Estrogen prevents anti-tumor effects of Zoledronic acid in breast cancer through the NK and CD8+T cell PD-1/PD-L1 axes

George C, Zhou J, Canuas-Landero V, Lefley D, Hughes R, Thistletwaite F, Wilson C, Holen I, Brown J, Dunning M, Danson S, Winter M, Quayle L, Muthana M, Ottewell P.   +14 more
europepmc   +1 more source