Results 221 to 230 of about 14,692,425 (274)

Sex-specific lymphatic responses to estrogen shape atherosclerosis in high-risk mice. [PDF]

Front Cardiovasc Med
Mesples M, Lacroix É, Tessier N, Farhat M, Milasan A, Babran S, Fernandez C, Latendresse T, Benoit J, Long V, Guillemette J, El Khakani S, Alikashani A, Leblanc CA, Higgins MÈ, Durocher-Granger V, Fiset C, Martel C.   +17 more
europepmc   +1 more source

Dynamic Supramolecular Polyurethane Elastomers Enabling Bioinspired Strain‐Adaptive Stiffening to Resolve the Softness–Strength Paradox

Advanced Science, EarlyView.
Segmental‐level molecular engineering of a supramolecular polyurethane elastomer integrates strain‐adaptive chains, soft elastic segments, and dynamic hydrogen bonding motifs. This design reconciles skin‐like softness with muscle‐level strength, offering a sustainable and high‐performance material platform for next‐generation artificial skin and soft ...
Haoming Zou, Zhi‐Xiong Fei, Zhao Yang, Ke‐Ke Yang, Dong‐Xu Yang, Ling‐Ying Shi   +5 more
wiley   +1 more source

Effects of varying concentrations of Ubiquinol (coenzyme Q10) on physiological parameters in male donkeys (<i>Equus asinus</i>). [PDF]

Front Vet Sci
Akhtar MF, Umar M, Changfa W.
europepmc   +1 more source

Molecularly Bridged Heterointerface Engineering: Designing Transparent, Wear‐Resistant, Hard yet Flexible Optoelectronic Protective Film

Advanced Science, EarlyView.
A molecular‐bridging heterogeneous interface engineering strategy is introduced to combine a polyhedral oligomeric silsesquioxane (POSS)‐based hard coating with a colorless polyimide (CPI)‐based flexible layer. The robust heterogeneous interface endows the integrated system with the superior properties of both layers and their synergistic ...
Huiyang Lu, Zihui Liu, Jianan Yuan, Yunhao Wei, Shuangfei Xiang, Qinghua Lu   +5 more
wiley   +1 more source

<i>In silico</i> reconstruction of a salmonid alphavirus virion reveals distinctive molecular features implicated in virulence. [PDF]

iScience
Biacchesi S, Fauvet C, Mérour E, Bernard J, Lamoureux A, Lallias D, Millet JK.   +6 more
europepmc   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

Advanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes, Xiaokang Jin, Miguel A. Campos, Chen Zhou, Xiaoyu Zhang   +4 more
wiley   +1 more source

Investigating antibody cross-reactivity and transmission dynamics of alphaviruses and flaviviruses using a multiplex serological assay. [PDF]

Nat Commun
Yman V, Rosado J, Ochida N, Garcia L, Gasasira MF, Baudemont G, Cramer E, Dupont-Rouzeyrol M, Huet K, Douine M, Sanna A, Lambert Y, Carrasco-Escobar G, Nolasco O, Gamboa D, Fall G, Ndiaye O, Faye O, Loucoubar C, Toure-Balde A, Niang M, Vigan-Womas I, Cauchemez S, White MT.   +23 more
europepmc   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Informed mutation of western equine encephalitis virus to heparan sulfate binding: Implications for rational design of alphavirus live attenuated vaccines. [PDF]

PLoS Pathog
Lukash T, Poudyal S, Gilliland TC, Klose T, Sun C, Vasilatos SN, Farren JL, Lam LKM, Kuhn RJ, Klimstra WB.   +9 more
europepmc   +1 more source