Results 201 to 210 of about 288,045 (238)

Neonatal-Onset Refractory Thrombocytopenia and Anemia Associated With a Homozygous In-Frame NFE2 Duplication. [PDF]

Am J Case Rep
Uddin MS, Albehair M, Alshammari FNM, Esmail A, Shafeen K, Bin Hassan A, Bawazier H.   +6 more
europepmc   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Prolonged oscillating preoptic area kisspeptin neuron activity underlies the preovulatory luteinizing hormone surge in mice. [PDF]

Elife
Zhou Z, Huang CY, Herbison AE.
europepmc   +1 more source

Asymmetric Electrostrain/Electrobending in Piezoelectric Ceramics: Role of Defect Dipoles or Oxygen Vacancies

Advanced Science, EarlyView.
Defect‐configurational origins of the asymmetric apparent electrostrain are revealed in different piezoelectric ceramics via atomic‐scale visualization of defect configurations. Migration of oxygen vacancies leads to the electrobending effect in N2‐sintered BaTiO3, while defect dipoles in Ba0.99TiO2.99 generate true asymmetric electrostrain without ...
Jie Wang, Geng Huangfu, Hongjie Zhang, Tiannan Yang, Zhenhua Ma, Jingsheng Chen, Yun Liu, Yiping Guo   +7 more
wiley   +1 more source

Hydrocarbon generation kinetics and history of source rocks in different salinity environments, Dongpu Depression, Bohai Bay Basin, China. [PDF]

PLoS One
Zhang C, Liu J, Xu T, Yang J, Lv L.
europepmc   +1 more source

Hierarchical Ordering Induced Ultrahigh Cryogenic Strength and Strain Hardening in a Ni2CoFeV Medium‐Entropy Alloy

Advanced Science, EarlyView.
A tri‐phase Ni2CoFeV medium‐entropy alloy with fcc, κ, and L12 phases achieves exceptional cryogenic strength‐ductility synergy at 77 K. It delivers a yield strength of 1.4 GPa, an ultimate tensile strength of 2.07 GPa and a tensile ductility of 28%.
Lei Gu, Wei Jiang, Qingzhong Mao, Xiang Chen, Yonghao Zhao   +4 more
wiley   +1 more source

Sex Hormone Imbalance in Keratoconus: Estrogen-Mediated Collagen Remodeling and Biomechanical Weakening. [PDF]

Invest Ophthalmol Vis Sci
Zhang M, Liu Y, Gao N, Ma Y, Li F, Li X, Cui M, Zhao S, Yang R.   +8 more
europepmc   +1 more source

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

Advanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang, Peipei Song, Xueji Wu, Lei Wang, Wei Xie, Pinning Feng, Chao Cheng, Jianping Guo   +7 more
wiley   +1 more source

Reproductive history differentially shapes the neural response of middle-aged hAPOEɛ4 female rats to estradiol therapy after a metabolic challenge. [PDF]

Biol Sex Differ
Richard JE, Mohammad A, Lieblich SE, Go KA, Wang S, Rechlin RK, Splinter TFL, Barreto GE, Galea LAM.   +8 more
europepmc   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source