Results 121 to 130 of about 645,781 (307)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Electromigration-induced resistance switching in indented Al microstrips

open access: yesNew Journal of Physics, 2019
Non-volatile resistive memory cells are promising candidates to tremendously impact the further development of Boolean and neuromorphic computing. In particular, nanoscale memory-bit cells based on electromigration (EM)-induced resistive switching in ...
J Lombardo   +5 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Inclusive and differential cross section measurements of t t ¯ b b ¯ $$ \textrm{t}\overline{\textrm{t}}\textrm{b}\overline{\textrm{b}} $$ production in the lepton+jets channel at s $$ \sqrt{s} $$ = 13 TeV

open access: yesJournal of High Energy Physics
Measurements of inclusive and normalized differential cross sections of the associated production of top quark-antiquark and bottom quark-antiquark pairs, t t ¯ b b ¯ $$ \textrm{t}\overline{\textrm{t}}\textrm{b}\overline{\textrm{b}} $$ , are presented ...
The CMS collaboration   +2362 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Measurement of the Higgs boson production via vector boson fusion and its decay into bottom quarks in proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV

open access: yesJournal of High Energy Physics
A measurement of the Higgs boson (H) production via vector boson fusion (VBF) and its decay into a bottom quark-antiquark pair ( b b ¯ $$ \textrm{b}\overline{\textrm{b}} $$ ) is presented using proton-proton collision data recorded by the CMS experiment ...
The CMS collaboration   +2325 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

B-physics: Theoretical predictions in the LHC era

open access: yes, 2008
We discuss the status of the theoretical predictions of some interesting b-physics observables that are sensitive to New Physics and can be measured at the ...
TARANTINO, CECILIA
core   +1 more source

Search for the decay B 0 → ϕϕ

open access: yesJournal of High Energy Physics
A search for the decay B 0 → ϕϕ is made using pp collision data collected with the LHCb detector at centre-of-mass energies of 7, 8 and 13 TeV, corresponding to an integrated luminosity of 9 fb −1. No significant signal is observed, and an upper limit on
The LHCb collaboration   +1187 more
doaj   +1 more source

Imprints of new physics operators in the semileptonic B→a1(1260)ℓ−ν¯ℓ process in SMEFT approach

open access: yesPhysics Letters B
At present, there are several measurements of B decays that exhibit discrepancies with the predictions of the Standard Model, and suggest the presence of new physics in b→s and b→c(u) quark level transitions.
Manas Kumar Mohapatra   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy