Results 171 to 180 of about 472,626 (351)

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Involvement of Microbiota in Insect Physiology: Focus on B Vitamins. [PDF]

mBio, 2023
Serrato-Salas J, Gendrin M.
europepmc   +1 more source

Identifying hemophilia B carriers: Utility of aPTT, factor IX levels and ratios of factor IX to other Vitamin K dependent factors [PDF]

Michael Shu, Caroline Malcolmson, Alessandra Bosch, Teodora Markovic, Cindy Wakefield, Vanessa Bouskill, Manuel Carção   +6 more
openalex   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

B Vitamins: Functions and Uses in Medicine. [PDF]

Perm J, 2022
Hanna M, Jaqua E, Nguyen V, Clay J.
europepmc   +1 more source

Vitamin B ₁₂ absorption in some neurological and neuroendocrine disorders [PDF]

, 1970
D. Donaldson, P. T. Lascelles
openalex   +1 more source

Vitamin B [PDF]

Nature, 1929
openaire   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Deficiency of B vitamins leads to cholesterol-independent atherogenic transformation of the aorta [PDF]

Biomed Pharmacother, 2022
Almer G, Opriessnig P, Wolinski H, Sommer G, Diwoky C, Lechleitner M, Kolb D, Bubalo V, Brunner M, Schwarz A, Leitinger G, Schoiswohl G, Marsche G, Niedrist T, Schauer S, Oswald W, Groselj-Strele A, Paar M, Cvirn G, Hoefler G, Rechberger G, Herrmann M, Frank S, Holzapfel G, Kratky D, Mangge H, Hörl G, Tehlivets O.   +27 more
europepmc   +2 more sources

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source