Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree +9 more
wiley +1 more source
چکیده در پیشینۀ آموزش زبان فارسی به غیرایرانیان شاهد این هستیم که دستور دارای بیشترین اهمیت بوده و بر خلاف سیر تکوین ها برنامه ی درسی، همچنان نیـز دارای بیشـترین اهمیـت اسـت . مـادام یکـه دستور محور آموزش زبان فارسی باشد، بحث دبن سطح ی آمـوزش زبـان پیچیـدگی خاصـ ی ایجـاد نمیکن ؛د زیرا سطحبندی محتوای دستوری تابع نیازهای صوری و غیـر ارتبـاطی اسـت و ...
openaire +1 more source
Editorial: Emergence of Cicada (BA.3.2) SARS-CoV-2 and the Implications for COVID-19 Surveillance and Monitoring. [PDF]
Parums DV.
europepmc +1 more source
Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven +16 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Xi-Zheng Li, Yu-Wen Yan, Hui-Zhong Zhang, Yan Zhang School of Nursing and Health, Zhengzhou University, Zhengzhou City, Henan Province, 450001, People’s Republic of ChinaCorrespondence: Yan Zhang, School of Nursing and Health, Zhengzhou University, No ...
Li XZ, Yan YW, Zhang HZ, Zhang Y
doaj
Selected immunoendocrine and performance adaptations to upper-body plyometric training and β-alanine supplementation in male swimmers. [PDF]
Gao H, Yu X, Guo Z.
europepmc +1 more source
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Research advances in the application of betulinic acid for anti-inflammatory and anti-tumour therapy. [PDF]
Chu Z +7 more
europepmc +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source

