Results 1 to 10 of about 3,484 (170)

What Babesia microti Is Now [PDF]

Pathogens, 2021
Parasites from diverse hosts morphologically identified as Babesia microti have previously been shown to belong to a paraphyletic species complex. With a growing number of reports of B. microti-like parasites from across the world, this paper seeks to report on the current knowledge of the diversity of this species complex. Phylogenetic analysis of 18S
Heidi K Goethert
exaly   +4 more sources

Evolutionary analysis of Babesia vulpes and Babesia microti-like parasites

Parasites & Vectors, 2022
Background The Babesia microti-like parasite is an emerging tick-borne piroplasm that has been detected in a range of hosts worldwide. Babesia vulpes, which is found in dogs and foxes, has been reclassified from B. microti-like parasites.
Sanghyun Lee, Yeonchul Hong, Dong-Il Chung, Hyung-Kwan Jang, Youn-Kyoung Goo, Xuenan Xuan   +5 more
doaj   +3 more sources

A Novel Thioredoxin-Like Protein of Babesia microti Involved in Parasite Pathogenicity

Frontiers in Cellular and Infection Microbiology, 2022
Babesiosis poses a serious threat to immunocompromised individuals and the major etiological species of Babesia for human babesiosis is Babesia microti. Merozoites are a critical stage in the life cycle of Babesia microti. Several merozoite proteins have
Xianyu Piao, Nan Hou, Qijun Chen
exaly   +3 more sources

A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection [PDF]

Parasites & Vectors, 2023
Background The protozoan parasite Babesia microti that causes the zoonotic disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle.
Yao Wang, Qianqian Zhang, Wanruo Zhang, Junhu Chen, Jianfeng Dai, Xia Zhou   +5 more
doaj   +2 more sources

A Set of Rapid Diagnostic Tool for Babesia microti Infection. [PDF]

J Clin Lab Anal
This study develops a cross‐priming amplification combined with vertical flow visualization (CPA‐VF) assay for rapid, low‐cost detection of Babesia microti, achieving a detection limit of 2.56 fg/reaction (equivalent to 0.000004% parasitic red blood cells) with 95.5% sensitivity and specificity compared to nested PCR.
Bai Y, Zhang S, Liang Q, Zhang X, Liu Z, Ye Y, Luo J, Yin H, You C, Guan G, Wang J.   +10 more
europepmc   +2 more sources

In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments. [PDF]

Adv Sci (Weinh)
Here, an open microfluidic platform termed “µ‐Blood” is reported for real‐time, continuous monitoring of Babesia microti infection dynamics in vitro. µ‐Blood allows direct interrogation of whole blood with preserved integrity of the original whole blood microenvironment through an extended period (e.g., 72 h with mouse red blood cells) ex vivo. µ‐Blood
Li C, Bache EG, Apgar AL, Tufts DM, Niepa THR.   +4 more
europepmc   +2 more sources

Persistence of Babesia microti Infection in Humans [PDF]

Pathogens, 2019
Persistent infection is a characteristic feature of babesiosis, a worldwide, emerging tick-borne disease caused by members of the genus Babesia. Persistence of Babesia infection in reservoir hosts increases the probability of survival and transmission of these pathogens.
Evan M Bloch, Sanjai Kumar, Peter J Krause   +2 more
exaly   +4 more sources

Structural and Functional Characterization of the 28 kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti. [PDF]

Proteins
ABSTRACT Babesiosis is a tick‐borne disease that poses a significant threat to animal health worldwide. In addition, climate change and the risk of human‐to‐human transmission through blood transfusion have made babesiosis an emerging disease in humans.
Mouhand A, Pissarra J, Barthe P, Roumestand C, Delbecq S.   +4 more
europepmc   +2 more sources

Design and screening of novel molecular compounds targeting lactate dehydrogenase of Babesia microti [PDF]

Parasites & Vectors
Background Human babesiosis is caused by several species within the Babesia genus, primarily Babesia microti, Babesia duncani, and Babesia divergens, all of which infect human red blood cells (RBCs).
Wanxin Luo, Long Yu, Shiyu Lu, Yuxin Yu, Yidan Bai, Sen Wang, Dongfang Li, Zhen Han, Yaxin Zheng, Fangjie Li, Junlong Zhao, Lan He   +11 more
doaj   +2 more sources

Continuous in vitro propagation of Babesia microti. [PDF]

Infect Immun
ABSTRACT The currently accepted initiation of Babesia infection describes a sporozoite stage infused into the host, along with other saliva components, by the tick vector. This sporozoite can enter and initiate erythrocyte infection directly. In the particular case of Babesia microti
Fuller L.
europepmc   +3 more sources