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What Babesia microti Is Now [PDF]
Pathogens, 2021 Parasites from diverse hosts morphologically identified as Babesia microti have previously been shown to belong to a paraphyletic species complex. With a growing number of reports of B. microti-like parasites from across the world, this paper seeks to report on the current knowledge of the diversity of this species complex. Phylogenetic analysis of 18S
Heidi K. Goethert
exaly +4 more sources
Babesia microti: Breaking the culture barrier. [PDF]
Trends ParasitolBabesia microti poses a significant threat to human health, underscoring the need for an improved in vitro culture system to reduce reliance on animal models and support drug and vaccine screening. Key challenges include the tropism of preferential host red blood cells (RBCs), parasite metabolic needs, culture medium formulation, and optimization of ...
Vydyam P, Beri D, Lobo CA.
europepmc +3 more sources
Persistence of Babesia microti Infection in Humans [PDF]
Pathogens, 2019 Persistent infection is a characteristic feature of babesiosis, a worldwide, emerging tick-borne disease caused by members of the genus Babesia. Persistence of Babesia infection in reservoir hosts increases the probability of survival and transmission of these pathogens.
Sanjai Kumar +2 more
exaly +4 more sources
Continuous in vitro propagation of Babesia microti. [PDF]
Infect ImmunABSTRACT The currently accepted initiation of Babesia infection describes a sporozoite stage infused into the host, along with other saliva components, by the tick vector. This sporozoite can enter and initiate erythrocyte infection directly. In the particular case of Babesia microti
Fuller L.
europepmc +3 more sources
Transient Transfection of the Zoonotic Parasite Babesia microti [PDF]
Pathogens, 2020 The development of genetic manipulation techniques has been reported in many protozoan parasites over the past few years. However, these techniques have not been established for Babesia microti. Here, we report the first successful transient transfection of B. microti. The plasmids containing the firefly luciferase reporter gene were transfected into B.
Yongchang Li +2 more
exaly +4 more sources
Babesia microti acquired in Canada [PDF]
Canadian Medical Association Journal, 2021 KEY POINTS In August 2019, a 75-year-old man presented to the emergency department in Winnipeg with a 6-week history of fever, myalgia, lethargy and 7-kg weight loss. After 3 weeks of symptoms, he had visited his family physician, who prescribed a 1-week course of amoxicillin–clavulanic acid ...
Yang, Jiayu +2 more
openaire +2 more sources
Presence and Identity Of Babesia Microti In Ireland
Ticks and Tick-borne Diseases, 2023 Babesia microti is a tick-transmitted protozoan parasite of wildlife that can also cause serious disease in humans. It is now well established that B. microti represents an assemblage of different strains or species, only some of which are important zoonotic pathogens.
Zintl, A. +8 more
openaire +5 more sources
Establishment of a stable transfection method in Babesia microti and identification of a novel bidirectional promoter of Babesia microti [PDF]
Scientific Reports, 2020 AbstractBabesia microti, an emerging human pathogen, is primarily transmitted through a bite of an infected tick and blood transfusions in human. Stable transfection technique has been reported in many protozoan parasites over the past few years. However, in vivo transient and stable transfection method has not been established for Babesia microti ...
Jaijyan, Dabbu Kumar +4 more
openaire +2 more sources
Babesia Microti – Known and Unknown Protists [PDF]
Global Journal of Zoology, 2017 B. microti is known as the main etiological agent of human babesiosis and there are some case studies for that disease, highlighting the fact that this is an important “emerging tick-borne disease”.
Albertyńska, Marta +4 more
openaire +4 more sources
Evolutionary analysis of Babesia vulpes and Babesia microti-like parasites
Parasites & Vectors, 2022 Abstract Background The Babesia microti-like parasite is an emerging tick-borne piroplasm that has been detected in a range of hosts worldwide. Babesia vulpes, which is found in dogs and foxes, has been reclassified from B. microti-like parasites. The relationships among these B. microti-like parasites and B.
Sanghyun Lee +5 more
openaire +3 more sources