Ubiquitous late competence genes in Bacillus species indicate the presence of functional DNA uptake machineries [PDF]
P>Natural competence for genetic transformation, i.e. the ability to take up DNA and stably integrate it in the genome, has so far only been observed in the bacterial kingdom (both in Gram-negative and Gram-positive species) and may contribute to ...
Kovacs, Akos T. +4 more
core +3 more sources
Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539
The manganese sensor DR2539 from Deinococus radiodurans recognises the dr1709 promoter region, which consists of a 21 base pair pseudo‐palindrome binding two DR2539 monomers. Here, we identified four manganese binding sites and investigated protein‐DNA interactions, with critical nucleotides being probed.
Cristiano Mota +7 more
wiley +1 more source
In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate [PDF]
Background HIV-1 integrase (IN) is an emerging drug target, as IN strand transfer inhibitors (INSTIs) are proving potent antiretroviral agents in clinical trials.
Andrea Savarino
core +1 more source
Overexpression of endogenous multi‐copper oxidases mcoA and mcoC in Rhodococcus jostii RHA1 was found to enhance production of 2,4‐pyridine‐dicarboxylic acid from soda lignin by 2.5‐ and 3.5‐fold, respectively. This approach provides an opportunity to enhance titres of lignin‐derived bioproducts. Abstract To improve the titre of lignin‐derived pyridine‐
Goran M. M. Rashid +3 more
wiley +1 more source
Microbial β-Glucosidases: screening, characterization, cloning and applications [PDF]
Cellulose is the most abundant biomaterial in the biosphere and the major component of plant biomass. Cellulase is an enzymatic system required for conversion of renewable cellulose biomass into free sugar for subsequent use in different applications ...
Ahmed, Amer +5 more
core
Isolation, purification, and characterization of xylanase produced by three species of bacillus under submerged fermentation conditions [PDF]
This study focuses on the screening and identification of bacteria, which can produce alkaline xylanase at alkaline pH and high temperature. Bacterial isolates from enriched decaying soil, capable of hydrolyzing xylan were screened. Selected and purified
Chandra, Khushboo, Yadav, Bhuvnesh
core +2 more sources
The goal of the study is to evaluate metabolic and morphological changes of the facultative alkaliphile Bacillus aequororis 5‐DB and the weakly alkali‐resistant B. subtilis ATCC 6633 in a wide pH range and at different NaCl concentrations. The alkaliphile B. aequororis 5‐DB is shown to have a broader general resistance to adverse factors (wide pH range,
Yuliya Maksimova +3 more
wiley +1 more source
Background Xylan is the major component of hemicelluloses, which are the second most abundant polysaccharides in nature, accounting for approximately one-third of all renewable organic carbon resources on earth.
Xueqiang Liu +5 more
doaj +1 more source
Widespread occurrence of non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase among gram-positive bacteria [PDF]
The non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase (GAPDHN, NADP+-specific, EC 1.2.1.9) is present in green eukaryotes and some Streptococcus strains.
Abdelaziz Soukri +4 more
core +2 more sources
Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii [PDF]
ACKNOWLEDGMENTS We acknowledge support from BBSRC grant no. BB/L009951/1, from the Scottish government Food, Land and People program, and from the Society for Applied Microbiology. E.A.B. is supported by a grant (no.
Bayer, Edward A. +11 more
core +4 more sources

