Results 61 to 70 of about 537,633 (307)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Materials Research LettersThe Bauschinger effect, characterized by a reduction in yield stress upon load reversal, plays a critical role in both springback prediction and the understanding of back stress-mediated strengthening in emerging heterostructured materials. In this study,
Gang Hee Gu, Yongju Kim, Hyoung Seop Kim
doaj +1 more source
Stress Distribution and Fluctuation Cycle on the Rack Face of the Rock Cutting Tool
Shock and Vibration, 2019 The distribution of the stress field on the rack face has significant impacts on the performance and service life of the rock cutting tool. A dynamic simulation model of the stress on the rock cutting tool is established by finite element code Abaqus ...
Xiaofeng Yang +2 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Low-Cost Wearable for Fatigue and Back-Stress Measurement in Nursing
, 2016 In recent years the need for informal home care in European countries is growing quickly due to increased life expectancy and demographic change. Informal caregivers have to overcome many obstacles ranging from a lack of adequate training to misjudging their physical and psychological abilities.
Baquapuri, Halim I. +4 more
openaire +3 more sources
Effects of the grain size and shape on the flow stress: A dislocation dynamics study [PDF]
, 2019 Dislocation dynamics simulation is used to investigate the effect of grain size and grain shape on the flow stress in model copper grains. We consider grains of 1.25-10 $\mu$m size, three orientations (, and ) and three shapes (cube, plate and needles).
Devincre, Benoit +2 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
PLoS ONE, 2019 Stress can impair cognitive performance, as commonly observed in cognitive performance anxiety (CPA; e.g., test anxiety). Cognitive theories indicate that stress impairs performance by increasing attention to negative thoughts, a phenomenon also known as
Angelos Angelidis +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Non-proportional deformation paths for sheet metal: experiments and models [PDF]
, 2009 For mild steel, after significant plastic deformation in one direction, a subsequent deformation in an orthogonal direction shows a typical stress overshoot compared to monotonic deformation. This phenomenon is investigated experimentally and numerically
Boogaard, A.H. van den, Riel, M. van
core +2 more sources