Results 61 to 70 of about 5,205,464 (320)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Student Participation in Online Content-Related Discussion and Its Relation to Students’ Background Knowledge

open access: yesEducation Sciences, 2020
This paper presents two novel network methods developed for education research. These methods were used to investigate online discussions and the structure of students’ background knowledge in a blended university course for pre-service teachers (n = 11).
Miikka Turkkila, Henri Lommi
doaj   +1 more source

Using background knowledge to rank itemsets [PDF]

open access: yesData Mining and Knowledge Discovery, 2010
Assessing the quality of discovered results is an important open problem in data mining. Such assessment is particularly vital when mining itemsets, since commonly many of the discovered patterns can be easily explained by background knowledge. The simplest approach to screen uninteresting patterns is to compare the observed frequency against the ...
Tatti, Nikolaj, Mampaey, Michael
openaire   +3 more sources

Accessing Background Knowledge To Build Mathematical Vocabulary [PDF]

open access: yes, 2007
This paper examines the benefits of accessing knowledge to build background knowledge in mathematics. Various methods of vocabulary instruction are explained and examined.
Sodeman, Stephanie
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Logics for qualitative inductive generalization [PDF]

open access: yes, 2010
The paper contains a survey of (mainly unpublished) adaptive logics of inductive generalization. These defeasible logics are precise formulations of certain methods.
Batens, Diderik
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

IMPROVEMENT OF SOCIAL AND CULTURAL PREPARATION OF LINGUISTS-STUDENTS IN THE PROCESS OF FOREIGN LANGUAGE TEACHING

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2016
The notions social and cultural competence, background and ethnic-cultural knowledge, intercultural sensibility are analyzed. It is shown that the lack or insufficient formation of social and cultural competence among students-linguists is the reason of ...
Iraida Evgenevna Bryksina
doaj   +1 more source

Background Knowledge and Translation Ability [PDF]

open access: yesMatn/Pizhūhī-i Adabī, 1998
In recent decades, i11 most cases information transfer depends on flicie11t translation. However, most of tire rendered materials are incomprehensible and this is due to many factors such as deficiencies in tire translator "background knowledge qf ...
parviz birjandi, R. amin zadeh
doaj   +1 more source

Home - About - Disclaimer - Privacy