Results 71 to 80 of about 1,929,471 (312)

The spectrum of the 2D Black Hole, or Does the 2D black hole have tachyonic or W--hair? [PDF]

, 1993
We solve the equations of motion of the tachyon and the discrete states in the background of Witten's semiclassical black hole and in the exact 2D dilaton-graviton background of Dijkgraaf et al.
Akhoury, Banks, Bouwknegt, Brustein, Callan, Das, David, de Alwis, Diamandis, Dijkgraaf, Distler, Distler, Eguchi, Elitzur, Ellis, Gradshteyn, Ishikawa, Itoi, Jack, Klebanov, Knizhnik, Lian, Mandal, Marcus, Neil Marcus, Polyakov, Seiberg, Tseytlin, Wakimoto, Witten, Witten, Yaron Oz   +31 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A review on the prevention of inflammatory periimplant diseases [PDF]

, 2019
Background: An impressive number of dental implants are inserted worldwide. Evolution in dental implants and simplification of surgical techniques allowed a significant increase in the number of dentists involved in implant surgery.
Di Nardo, D., Passariello, C., Polimeni, A., Testarelli, L.   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Application of MMS Data to Road Bridge Maintenance Management [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
In Japan, as many road structures age and labor shortages arising from a declining birthrate and aging population coincide with increasingly severe disasters, there is a growing need for efficient maintenance management. I-Construction 2.0 is progressing,
T. Misaki, K. Ogawa, S. Nishiyama, M. Yamamoto, K. Kimoto   +4 more
doaj   +1 more source

Some Properties of Bilingual Maintenance and Loss in Mexican Background High-School Students

Applied Linguistics, 1992
Properties of maintenance and loss of Spanish/English bilingualism were investigated in 308 high school students of Mexican background. Key variables investigated included: (1) actual and self-reported proficiencies in Spanish and English; (2) self-reported language choice behavior in various settings; and (3) language attitude.
H. KENJI, D. D'ANDREA
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Iodine and Iron Deficiency in Mild Iodine Deficiency Region Under Iodine Supplementation

Клиническая и экспериментальная тиреоидология, 2005
Objectives: Studying epidemiological criteria deficiency of iron and iodine at the population of Tyumen, on a background of iodine preventive maintenance. Methods: Because iron deficiency may impair the efficacy of iodine supplementation, the aim of this

doaj   +1 more source

A qualitative study on the background of long-term maintenance patients at a private Japanese dental clinic [PDF]

BMC Oral Health, 2016
Continued periodontal maintenance after active therapy is highly important for maintaining a healthy oral function. In Japan, the rate of consultation for periodontal maintenance is remarkably low compared to other developed countries. This study analyzed the relationship between long-term maintenance and patient background characteristics in an effort
Kato, Tomotaka, Sugiyama, Seiichi, Makino, Michiko, Naito, Toru   +3 more
openaire   +2 more sources