Results 41 to 50 of about 106,224 (286)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Fractal Numerical Investigation of Mixed Convective Prandtl-Eyring Nanofluid Flow with Space and Temperature-Dependent Heat Source

Fractal and Fractional
An explicit computational scheme is proposed for solving fractal time-dependent partial differential equations (PDEs). The scheme is a three-stage scheme constructed using the fractal Taylor series. The fractal time order of the scheme is three.
Yasir Nawaz, Muhammad Shoaib Arif, Muavia Mansoor, Kamaleldin Abodayeh, Amani S. Baazeem   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

ILL-POSEDNESS AND STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH DIRICHLET AND INTEGRAL BOUNDARY CONDITIONS

Tạp chí Khoa học
In this paper, we first prove that the heat equation backward in time with Dirichlet and integral boundary conditions is an ill- posed problem. Then, we establish a stability estimate of Hölder type for this ill-posed problem.
Nguyen Van Duc, Phan Hoai Linh
doaj   +1 more source

Numerical simulation of Burgers’ equation using cubic B-splines

Nonlinear Engineering, 2017
In this paper, a numerical θ scheme is proposed for solving nonlinear Burgers’ equation. By employing Hopf-Cole transformation, the nonlinear Burgers’ equation is linearized to the linear Heat equation.
Lakshmi C., Awasthi Ashish
doaj   +1 more source

Sequential Implicit Numerical Scheme for Pollutant and Heat Transport in a Plane-Poiseuille Flow [PDF]

Journal of Applied and Computational Mechanics, 2020
A sequential implicit numerical scheme is proposed for a system of partial differential equations defining the transport of heat and mass in the channel flow of a variable-viscosity fluid.
Chinedu Nwaigwe
doaj   +1 more source

Quantum fluctuation theorems for arbitrary environments: adiabatic and non-adiabatic entropy production [PDF]

, 2018
We analyze the production of entropy along non-equilibrium processes in quantum systems coupled to generic environments. First, we show that the entropy production due to final measurements and the loss of correlations obeys a fluctuation theorem in ...
Horowitz, Jordan M., Manzano, Gonzalo, Parrondo, Juan M. R.   +2 more
core   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH NEUMANN AND INTEGRAL BOUNDARY CONDITIONS

Tạp chí Khoa học
In this paper, we first prove that the heat equation backward in time with Neumann and integral boundary conditions is an ill-posed problem. Then, we establish a stability estimate of Hölder type for this ill-posed problem.
Nguyen Van Duc
doaj   +1 more source

A Meshless Method Based on the Fundamental Solution and Radial Basis Function for Solving an Inverse Heat Conduction Problem

Advances in Mathematical Physics, 2015
We propose a new meshless method to solve a backward inverse heat conduction problem. The numerical scheme, based on the fundamental solution of the heat equation and radial basis functions (RBFs), is used to obtain a numerical solution.
Muhammad Arghand, Majid Amirfakhrian
doaj   +1 more source