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Pediatric Emergency Care, 2017 Abstract Intrathecal baclofen therapy, given via an implanted pump in the abdominal wall either as a continuous infusion or bolus dosing, has been used for more than 25 years to treat the spasticity and dystonia associated with various brain and spinal cord conditions.
Carl R Baum
exaly +6 more sources
, 2005 Neurosurgical interventions have been brought into wide use during the past 10 to 15 years. The first is that of dorsal root rhizotomies, which has met with mixed reviews. Recent meta-analysis of affected patients demonstrates that if there is any benefit it is only in a few points of improvement and not dramatic functional improvements.
Maura Mcmanus
exaly +4 more sources
Baclofen Stability up to One Year in In Vivo Intrathecal Infusion Pumps [PDF]
Neuromodulation, 2023 Objectives: Commercial intrathecal baclofen treatment (ITBT) infusion pumps are recommended to be refilled within a maximum of 180 days, thus necessitating at least twice-yearly outpatient visits and refill injections.
Tommi K Korhonen +2 more
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A Novel Approach to Avoid Baclofen Withdrawal When Faced With Infected Baclofen Pumps
Neuromodulation, 2019Intrathecal (IT) Baclofen is beneficial for spasticity, but if pumps become infected necessitating removal, baclofen withdrawal is difficult to manage and life-threatening. Furthermore there is no consistency between dosing and severity of withdrawal. Case reports detail full baclofen withdrawal at dosages of 260 μg/day.To demonstrate that in patients ...
Vishad Sukul +2 more
exaly +3 more sources
Baclofen toxicity in an 8-year-old with an intrathecal baclofen pump
The Journal of Emergency Medicine, 2004Baclofen delivered by intrathecal pumps (ITB) is increasingly being utilized in the pediatric population, however, resources and education to support problems with these devices are limited. Typical management strategies for systemic baclofen overdose include removal of baclofen from the device reservoir or removal of cerebrospinal fluid from the ...
Ronald N, Yeh +3 more
openaire +2 more sources
Interaction of ventriculoperitoneal shunt and baclofen pump
Child's Nervous System, 2007The authors present three cases of children with shunted hydrocephalus and intrathecal delivery of baclofen via an implanted pump. Each case illustrates a potential interaction of these devices.A review of the pertinent charts, operative notes, and discharge summaries was performed, along with examination of the pertinent literature.The first case ...
Daniel H, Fulkerson +2 more
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Journal of toxicology. Clinical toxicology, 2003
Intrathecal baclofen is used as a muscle relaxant and antispasmodic in cases of spasticity resulting from central nervous system trauma. The baclofen withdrawal syndrome may include hyperthermia, tachycardia, hypertension, seizures, altered mental status, and psychomotor agitation.
Michael I, Greenberg +1 more
openaire +3 more sources
Intrathecal baclofen is used as a muscle relaxant and antispasmodic in cases of spasticity resulting from central nervous system trauma. The baclofen withdrawal syndrome may include hyperthermia, tachycardia, hypertension, seizures, altered mental status, and psychomotor agitation.
Michael I, Greenberg +1 more
openaire +3 more sources
Complications of Intrathecal Baclofen Pumps in Children
Pediatric Neurosurgery, 2003Intrathecal baclofen is increasingly being used to manage severe spasticity in children. Although substantial tone reduction with this treatment has been documented, complications also occur. In this study, we describe the device- and major non-device-related complications in a group of 100 consecutive children and young adults who received 117 ...
Judith L, Gooch +4 more
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Intrathecal Baclofen Pump Use for Spasticity
American Journal of Physical Medicine & Rehabilitation, 2000To obtain information from continuous intrathecal baclofen infusion (CIBI) pump centers regarding specific clinical practices and experiences.A total of 115 centers were surveyed by mail.Forty centers (35%) responded with information about 1,002 test doses and 936 pump placements. Patient diagnoses included cerebral palsy, spinal cord injury, traumatic
L, Stempien, T, Tsai
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Intrathecal baclofen pump implantation during pregnancy
Neurology, 2003Spasticity is a common, potentially disabling complication of spinal cord injury (SCI) that may be exacerbated by pregnancy. Twelve percent of women who become pregnant following SCI report a worsening of their spasticity during pregnancy and 15% have “significantly increased spasticity” during labor.1 Yet there is minimal research available concerning
A G, Roberts +6 more
openaire +2 more sources