Results 91 to 100 of about 263 (110)
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Pharmacology Biochemistry and Behavior, 2013
In the present study, the antidepressant-like effect of bacopaside I, a saponin compound present in the Bacopa monniera plant, was evaluated by behavioral and neurochemical methods. Bacopaside I (50, 15 and 5 mg/kg) was given to mice via oral gavage for 7 successive days.
Xiaojun Liu +2 more
exaly +3 more sources
In the present study, the antidepressant-like effect of bacopaside I, a saponin compound present in the Bacopa monniera plant, was evaluated by behavioral and neurochemical methods. Bacopaside I (50, 15 and 5 mg/kg) was given to mice via oral gavage for 7 successive days.
Xiaojun Liu +2 more
exaly +3 more sources
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2016
Bacopaside I is one of the main pseudojujubogenin glycosides isolated from Bacopa monniera. In the present study, a rapid and robust LC-ESI-MS/MS method was developed and validated to quantify bacopaside I in rat plasma. After plasma samples were deproteinized by methanol, the post-treatment samples were analyzed on a Zorbax Eclipse Plus C18 (2.1×50mm,
Kun Xiong
exaly +3 more sources
Bacopaside I is one of the main pseudojujubogenin glycosides isolated from Bacopa monniera. In the present study, a rapid and robust LC-ESI-MS/MS method was developed and validated to quantify bacopaside I in rat plasma. After plasma samples were deproteinized by methanol, the post-treatment samples were analyzed on a Zorbax Eclipse Plus C18 (2.1×50mm,
Kun Xiong
exaly +3 more sources
Phytochemical Analysis, 2012
ABSTRACTIntroductionBacopa monnieri (BM) contains several dammarane‐type triterpenoid saponins including bacopaside I and bacoside A. These bioactive compounds may be used as chemical markers for the quality control of different BM products used for promoting mental health and intellect.ObjectiveQuantification of bacopaside I and bacoside A in crude ...
Pratibha, Srivastava +3 more
openaire +2 more sources
ABSTRACTIntroductionBacopa monnieri (BM) contains several dammarane‐type triterpenoid saponins including bacopaside I and bacoside A. These bioactive compounds may be used as chemical markers for the quality control of different BM products used for promoting mental health and intellect.ObjectiveQuantification of bacopaside I and bacoside A in crude ...
Pratibha, Srivastava +3 more
openaire +2 more sources
Industrial Crops and Products, 2017
Abstract Bacopa monnieri (Brahmi) is a high value herbaceous medicinal species used for improving intellect and memory. In India, high demand of B. monnieri for the manufacture of herbal extracts and medicines prompts its collection in huge quantities from wild habitats, leading to the extinction of its genotypes. Wild accessions of B.
Anil John Johnson, Sabulal Baby
exaly +2 more sources
Abstract Bacopa monnieri (Brahmi) is a high value herbaceous medicinal species used for improving intellect and memory. In India, high demand of B. monnieri for the manufacture of herbal extracts and medicines prompts its collection in huge quantities from wild habitats, leading to the extinction of its genotypes. Wild accessions of B.
Anil John Johnson, Sabulal Baby
exaly +2 more sources
Journal of Pharmaceutical and Biomedical Analysis, 2016
Bacopaside I (BP-I) is the major pseudojujubogenin glycoside of Bacopa monniera (BM) extract which has been widely used as a nerve tonic to improve the memory and intellect of human beings from ancient times. A selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of BP-I in mouse plasma and ...
Manisha Bhateria +2 more
exaly +3 more sources
Bacopaside I (BP-I) is the major pseudojujubogenin glycoside of Bacopa monniera (BM) extract which has been widely used as a nerve tonic to improve the memory and intellect of human beings from ancient times. A selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of BP-I in mouse plasma and ...
Manisha Bhateria +2 more
exaly +3 more sources
Tissue Barriers
Bacopaside I (BM4), a saponin found in Bacopa monnieri, has nootropic, neuroprotective, and anti-depressant properties. Neuroprotective entities generally are impermeable across the brain membrane, and this hassle can be resolved by using drug-encapsulated polymeric nanoparticles (NPs).
Vini C Sekhar +2 more
exaly +3 more sources
Bacopaside I (BM4), a saponin found in Bacopa monnieri, has nootropic, neuroprotective, and anti-depressant properties. Neuroprotective entities generally are impermeable across the brain membrane, and this hassle can be resolved by using drug-encapsulated polymeric nanoparticles (NPs).
Vini C Sekhar +2 more
exaly +3 more sources
Journal of Molecular Graphics and Modelling
Aquaporin-1 (AQP1),a key water channel protein, is aberrantly overexpressed in multiple malignancies, rendering it a compelling therapeutic target. The natural products Bacopaside I and Bacopaside II have demonstrated inhibitory activity against AQP1, yet their molecular mechanisms remain elusive.
Mingyu Wei +9 more
openaire +2 more sources
Aquaporin-1 (AQP1),a key water channel protein, is aberrantly overexpressed in multiple malignancies, rendering it a compelling therapeutic target. The natural products Bacopaside I and Bacopaside II have demonstrated inhibitory activity against AQP1, yet their molecular mechanisms remain elusive.
Mingyu Wei +9 more
openaire +2 more sources
Journal of Ethnopharmacology, 2015
Bacopa monnieri (L.) Wettst. (BM) is a medicinal plant which has been not only used as a traditional medicine to improve intelligence and memory but also taken as vegetables in Vietnam for a long time. We previously demonstrated that Bacopa monnieri (BM) alcohol extract attenuated olfactory bulbectomy-induced cognitive deficits and the deterioration of
Xoan Thi, Le +6 more
openaire +2 more sources
Bacopa monnieri (L.) Wettst. (BM) is a medicinal plant which has been not only used as a traditional medicine to improve intelligence and memory but also taken as vegetables in Vietnam for a long time. We previously demonstrated that Bacopa monnieri (BM) alcohol extract attenuated olfactory bulbectomy-induced cognitive deficits and the deterioration of
Xoan Thi, Le +6 more
openaire +2 more sources
Phytomedicine
Aquaporin 1 (AQP1) is a promising target for regulating fibroblast-like synoviocyte (FLS) behaviors in rheumatoid arthritis (RA). Bacopaside I (BSI), the main active compound of the herbal medicine Bacopa monnieri with anti-RA effects, inhibits tumor cell growth by blocking AQP1, but its potential use in RA is unclear.To address BSI's anti-RA effects ...
Meng-Yuan Zhou
exaly +3 more sources
Aquaporin 1 (AQP1) is a promising target for regulating fibroblast-like synoviocyte (FLS) behaviors in rheumatoid arthritis (RA). Bacopaside I (BSI), the main active compound of the herbal medicine Bacopa monnieri with anti-RA effects, inhibits tumor cell growth by blocking AQP1, but its potential use in RA is unclear.To address BSI's anti-RA effects ...
Meng-Yuan Zhou
exaly +3 more sources
Phytotherapy Research
ABSTRACT Fibroblast‐like synoviocytes (FLS) drive rheumatoid arthritis (RA) progression. Bacopaside I (BSI), a major component of the anti‐RA herb Bacopa monnieri , demonstrates anti‐arthritic effects in RA animal models; however ...
Ling-Ling, Li +7 more
openaire +2 more sources
ABSTRACT Fibroblast‐like synoviocytes (FLS) drive rheumatoid arthritis (RA) progression. Bacopaside I (BSI), a major component of the anti‐RA herb Bacopa monnieri , demonstrates anti‐arthritic effects in RA animal models; however ...
Ling-Ling, Li +7 more
openaire +2 more sources