A Narrative Review on Rodent Models of Neuropsychopathology Associated with Low Temperature Exposure. [PDF]
Priya V, Ahmad F.
europepmc +1 more source
Promising Natural Remedies for Alzheimer's Disease Therapy. [PDF]
Thawabteh AM +6 more
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Utility of Multicellular Spheroids for Investigating Mechanisms of Chemoresistance in Triple-Negative Breast Cancer. [PDF]
Ncube KN +4 more
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<i>Trigonella foenum-graecum</i> L. protects against renal function decline in a mouse model of type 2 diabetic nephropathy by modulating the PI3K-Akt-ERK signaling pathway. [PDF]
Niu Y +8 more
europepmc +1 more source
Bacopaside I and II: two pseudojujubogenin glycosides from Bacopa monniera
Two saponins, designated as bacopaside I and II, have been isolated from Bacopa monniera Wettst. and their structures have been elucidated as 3-O-alpha-L-arabinofuranosyl-(1-->2)-[6-O-sulphonyl-beta-D-glucopyranosyl-(1-->3)]-alpha-L-arabinopyranosyl pseudojujubogenin (1) and 3-O-alpha-L-arabinofuranosyl-(1-->2)-[beta-D-glucopyranosyl (1-->3)]-beta-D ...
Ajit K Chakravarty +2 more
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Paraquat (PQ), an environmental neurotoxicant, causes acute fatal poisoning upon accidental or intentional ingestion (suicidal cases) worldwide. To date, an effective remedy for PQ toxicity is not available. In this study, we have evaluated the therapeutic efficacy of Bacopaside-I (BS-I), an active compound found in the plant extract of Bacopa monnieri
Surendra Kumar Anand +2 more
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Therapeutic options to contain seizures, a transitional stage of many neuropathologies, are limited due to the blood-brain barrier (BBB). Herbal nanoparticle formulations can be employed to enhance seizure prognosis. Bacoside A (BM3) and bacopaside I (BM4) were isolated from Bacopa monnieri and synthesized as nanoparticles (BM3NP and BM4NP ...
Vini C. Sekhar +5 more
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Immunochromatographic determination of bacopaside I in biological samples
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017We describe a novel immunochromatographic method for qualitative and quantitative analyses of bacopaside I, a bioactive constituent in Bacopa monnieri (L.) Wettst in biological samples. The assay was performed on polyethersulfone membrane using a polyclonal antibody raised against bacopaside I.
Dumrongsak Pekthong +2 more
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Bacopaside III, Bacopasaponin G, and Bacopasides A, B, and C from Bacopa monniera
Journal of Natural Products, 2002Two new saponins, 3-O-[6-O-sulfonyl-beta-d-glucopyranosyl-(1-->3)]-alpha-l-arabinopyranosyl pseudojujubogenin (1) and 3-O-[alpha-l-arabinofuranosyl-(1-->2)]-alpha-l-arabinopyranosyl jujubogenin (2), a new matsutaka alcohol derivative, (3R)-1-octan-3-yl-(6-O-sulfonyl)-beta-d-glucopyranoside (3), a new phenylethanoid glycoside, 3,4-dihydroxyphenylethyl ...
Chia-Chung, Hou +3 more
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Neuroprotective effects of bacopaside I in ischemic brain injury
Restorative Neurology and Neuroscience, 2013Purpose: Bacopa monnieri (L.) WETTST. is extensively used in traditional Indian medicine as a nerve tonic. The neuropharmacological properties of bacopaside I, an important component from B. monnieri, have not been studied so far. The present study investigated the effects and possible mechanisms of bacopaside I in a rat model of ...
Xiaojun, Liu +5 more
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