Results 41 to 50 of about 2,718,963 (248)

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.

Cell, 2015
The gastrointestinal (GI) tract contains much of the body's serotonin (5-hydroxytryptamine, 5-HT), but mechanisms controlling the metabolism of gut-derived 5-HT remain unclear.
J. Yano, Kristie B. Yu, Gregory P. Donaldson, Gauri G. Shastri, P. Ann, Liang Ma, C. Nagler, R. Ismagilov, S. Mazmanian, E. Hsiao   +9 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Infecção respiratória por bactérias do complexo Burkholderia cepacia: Evolução clínica em doentes com fibrose quística

Revista Portuguesa de Pneumologia, 2008
Resumo: O complexo Burkholderia cepacia (Bcc) é um grupo constituído por nove espécies de bactérias patogénicas oportunistas na fibrose quística (FQ), associadas a prognóstico mais reservado e a infecção cruzada entre os doentes. Existe grande heterogeneidade na deterioração pulmonar dos doentes colonizados/infectados com Bcc, evoluindo, por
Susana Correia, Catarina Nascimento, Luísa Pereira, Mónica V. Cunha, Isabel Sá-Correia, Celeste Barreto   +5 more
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sobrevivência de Xanthomonas axonopodis pv. manihotis em manipueira sob condições ambientais [PDF]

Pesquisa Agropecuária Brasileira, 2002
O objetivo deste trabalho foi avaliar a sobrevivência de um isolado de Xanthomonas axonopodis pv. manihotis (Xam), resistente ao sulfato de estreptomicina, em manipueira incubada em condições ambientais, em três épocas (março, julho e outubro de 2000 ...
Gustavo de Faria Theodoro, Antonio Carlos Maringoni   +1 more
doaj   +1 more source

An overview of the antimicrobial resistance mechanisms of bacteria

AIMS Microbiology, 2018
Resistance to antimicrobial agents has become a major source of morbidity and mortality worldwide. When antibiotics were first introduced in the 1900's, it was thought that we had won the war against microorganisms.
W. Reygaert
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Avaliaçâo da transmissão de Xanthomonas axonopodis pv. malvacearum via semente-algodoeiro em condições de campo, no cerrado sul-mato-grossense

Bioscience Journal, 2011
Avaliou-se a transmissão de Xanthomonas axonopodis pv. malvacearum (XAM) via semente-plântula de algodoeiro em condições de campo, no Cerrado sul-mato-grossense e por duas safras agrícolas (2009/10 e 2010/11).
Gustavo de Faria Theodoro, Hectory de Castro Correia, André Augusto Chumpati   +2 more
doaj