Results 71 to 80 of about 2,718,963 (248)

Reação de variedades e clones de laranjas a Xylella fastidiosa Reaction of oranges varieties and clones to Xylella fastidiosa

Revista Brasileira de Fruticultura, 2006
A clorose variegada dos citros (CVC) é uma doença grave, causada por Xylella fastidiosa. As medidas usuais de controle mostram-se pouco eficientes ou práticas e com alto custo.
Paulo Sergio de Souza, Antonio de Goes, Eduardo Sanches Stuchi, Elena Paola González Jaimes, Ester Wickert, Simone Rodrigues da Silva, Luiz Carlos Donadio   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Quantification of ruminal microbiota and production of methane and carbonic dioxide from diets with inclusion of glycerin

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
The aim of this study was to quantify the liquid-associated bacteria and protozoa of the rumen and to evaluate the potential of in vitro production of gases CH4 and CO2 of diets with inclusion of glycerin for sheep.
V.C. Santos, J.M.B. Ezequiel, A.C. Homem Junior, R.S.B. Pinheiro   +3 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Método de impregnação química aplicado em tubos microporosos e membranas tubulares para a microfiltração de emulsões e suspensões de bactérias Method of chemical impregnation applied to microporous tubes and tubular membranes for the microfiltration of emulsions and bacteria suspensions

Cerâmica, 2008
Uma técnica de impregnação química via solução de precursor foi desenvolvida para formação de filmes finos em tubos microporosos e membranas tubulares. O desempenho desta técnica foi analisado no processo de microfiltração de emulsões (óleo vegetal/água)
R. Del Colle, R. N. Haneda, E. Longo, M. J. Godinho, S. R. Fontes   +4 more
doaj   +1 more source

Bile salt biotransformations by human intestinal bacteria Published, JLR Papers in Press, November 18, 2005.

Journal of Lipid Research, 2006
Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels in the enterohepatic circulation of some individuals and may contribute to the pathogenesis of colon cancer, gallstones, and other gastrointestinal (GI) diseases.
Jason M. Ridlon, Daejoong Kang, P. Hylemon   +2 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Plant beneficial endophytic bacteria: Mechanisms, diversity, host range and genetic determinants.

Microbiology Research, 2019
Endophytic bacteria are the plant beneficial bacteria that thrive inside plants and can improve plant growth under normal and challenging conditions. They can benefit host plants directly by improving plant nutrient uptake and by modulating growth and ...
Imran Afzal, Z. Shinwari, S. Sikandar, S. Shahzad   +3 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Adenocarcinoma mucinoso gástrico associado a helicobacteriose e paracoccidioidomicose em cadela

Pubvet
 Tumores gástricos em cães são uma patologia pouco comum dentro das neoplasias, podendo se apresentar por diversos fatores como a presença de antígenos, neste âmbito, este material aborda aspectos morfológicos e histopatológicos de um caso de ...
Carla Sordi Furlanetto, Luiz Henrique Grisa, Wander Gawenda Ziger, Julia Da R. Tavares, Roberto Daniel Pizzolatto, Leticia Maria Santos Silva   +5 more
doaj   +1 more source