Results 121 to 130 of about 2,373,854 (304)

Unveiling and Assessing Antibiotic Misuse in Saudi Arabia—A Systematic Review and Meta-Analysis

open access: yesBacteria
Background: Antibiotic misuse and prescribing errors are significant concerns in clinical practice, contributing to unnecessary antibiotic exposure, increased adverse effects, rising healthcare costs, and the escalation of antibiotic resistance ...
Reena Almutairi   +9 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Shiga Toxin-Producing Escherichia coli in Poultry: Virulence, Antimicrobial Resistance, and Zoonotic Implications

open access: yesBacteria
Shiga toxin-producing Escherichia coli (STEC) is a major zoonotic foodborne pathogen associated with severe human illnesses, including hemorrhagic colitis and hemolytic uremic syndrome.
Arjmand Fatima, Muhammad Naeem
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Hysterangium mats and associated bacteria under eucalyptus gomphocephala in south-western Australia [PDF]

open access: yes, 2012
Eucalyptus gomphocephala (tuart) is an ecologically and culturally important woodland and forest tree native to south-western Australia. Unfortunately, tuart has been markedly declining in recent decades, and the mortality rate is as high as 90% in some ...
Dung, Nguyen Quang
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Microbial ecology of anammox bacteria in estuarine and oxygen minimum zone environments [PDF]

open access: yes
Anammox (anaerobic ammonium oxidation) is an environmentally significant process with great importance for global biogeochemical cycles. This process is mediated by a unique suite of phylogenetically distinct chemolithoautotrophic bacteria which ...
Williams, Simon
core  

Influence of Infection Origin, Type of Sampling, and Weather Factors on the Periodicity of Some Infectious Pathogens in Marseille University Hospitals, France

open access: yesBacteria
This study aimed at systematically exploring the seasonalities of bacterial identifications from 1 February 2014 to 31 January 2020 in hospitalized patients, considering the infectious site and the community-acquired or hospital-associated origin ...
Lanceï Kaba   +4 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

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