Results 91 to 100 of about 3,428,196 (309)

Retrospective Study of Canine Pathologies Causing Mortalities in Ilorin Kwara State, Nigeria [PDF]

Journal of Applied Veterinary Sciences
Canine pathologies refer to the various diseases, disorders, and abnormalities that can affect a dog’s different body systems and cause mortality. The primary aim of this study was to investigate the common pathologies that are associated with the ...
Mohammed Adam, Abdulateef Ajadi, Jamila Atata, Olatunde Akanbi, Shodeinde Shoyinka, Muhammad Abubakar, Moshood Olaniyi   +6 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Current microbiological pattern and role of respiratory syncytial virus infection in children with acute otitis media in South Jeddah

The Egyptian Journal of Otolaryngology, 2017
Introduction Otitis media is one of the most commonly encountered pediatric ENT diseases. Antibiotic resistance is increasing partly because of their overuse and largely because of changing microbiological strains leading to the disease.
Sherif K. Mohamed, Heba G. Hassan
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Universality in Bacterial Colonies

, 2011
The emergent spatial patterns generated by growing bacterial colonies have been the focus of intense study in physics during the last twenty years. Both experimental and theoretical investigations have made possible a clear qualitative picture of the ...
A. Cavagna, A.-L. Barabási, A.M. Lacasta, C.D. Nadell, C.D. Nadell, Carey D. Nadell, D.A. Kessler, E. Ben-Jacob, F. Family, H. Fujikawa, H. Fujikawa, H. Fujikawa, H. Shimada, I. Klapper, J. Monod, J. Wakita, J.A. Bonachela, J.B. Xavier, J.B. Xavier, J.B. Xavier, J.B. Xavier, J.M. López, J.M. López, J.M. López, João B. Xavier, Juan A. Bonachela, L.A.N. Amaral, L.R. Paiva, M. Cserzö, M. Eden, M. Kardar, M. Matsushita, M. Mimura, N. Kobayashi, N. Kobayashi, P. Meakin, R. Guimerà, R. Jullien, Simon A. Levin, T. Matsuyama, T. Vicsek, T.A. Witten Jr., U. Bastolla, Z. Csahók   +43 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Review of antimicrobial use and considerations in the elderly population

Clinical Interventions in Aging, 2018
Angela Giarratano,1 Samantha EL Green,1 David P Nicolau2 1Department of Pharmacy, Hartford Hospital, Hartford, CT, USA; 2Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA Abstract: Pharmacologic management of ...
Giarratano A, Green SEL, Nicolau DP
doaj  

Identification of putative new Escherichia coli flagellar antigens from human origin using serology, PCR-RFlP and DNA sequencing methods

Brazilian Journal of Infectious Diseases
Escherichia coli has been isolated frequently, showing flagellar antigens that are not recognized by any of the 53 antisera, provided by the most important reference center of E.
Monique Ribeiro Tiba, Claúdia de Moura, Marcelo Falsarella Carazzolle, Domingos da Silva Leite   +3 more
doaj   +1 more source