Results 71 to 80 of about 3,660,719 (365)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group B Streptococcus, 2020 [PDF]

Dataset version: Jul 2022; Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2020.

core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Soil bacterial networks are less stable under drought than fungal networks

Nature Communications, 2018
Soil microbial communities play a crucial role in ecosystem functioning, but it is unknown how co-occurrence networks within these communities respond to disturbances such as climate extremes. This represents an important knowledge gap because changes in
F. D. de Vries, R. Griffiths, M. Bailey, H. Craig, M. Girlanda, H. Gweon, S. Hallin, Aurore Kaisermann, A. Keith, Marina Kretzschmar, P. Lemanceau, E. Lumini, Kelly E. Mason, Anna E. Oliver, N. Ostle, J. Prosser, C. Thion, B. Thomson, R. Bardgett   +18 more
semanticscholar   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) report : Emerging Infections Program Network : Neisseria meningitidis, 2019 [PDF]

Citation: Centers for Disease Control and Prevention. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Neisseria meningitidis, 2019. www.cdc.gov/abcs/downloads/NMEN_Surveillance_Report_2019.pdfPublication date from document

core  

Retrospective Study of Canine Pathologies Causing Mortalities in Ilorin Kwara State, Nigeria [PDF]

Journal of Applied Veterinary Sciences
Canine pathologies refer to the various diseases, disorders, and abnormalities that can affect a dog’s different body systems and cause mortality. The primary aim of this study was to investigate the common pathologies that are associated with the ...
Mohammed Adam, Abdulateef Ajadi, Jamila Atata, Olatunde Akanbi, Shodeinde Shoyinka, Muhammad Abubakar, Moshood Olaniyi   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Active Bacterial Core surveillance (ABCs) surveillance areas/isolate collection [PDF]

The total population of Active Bacterial Core surveillance (ABCs) for invasive disease is approximately 44.1 million. However, most states further restrict the population for certain pathogens to ensure complete reporting.

core  

The Bacterial Cytoskeleton [PDF]

CBE—Life Sciences Education, 2006
One of the pleasures of teaching introductory biology courses is learning new things about old, familiar subjects … such as the differences between eukaryotes and prokaryotes. For a eukaryotic cell biologist, such learning usually entails examining how bacteria function, in ways other than how they replicate and transcribe DNA and how they synthesize ...
openaire   +2 more sources