Results 61 to 70 of about 1,726,519 (269)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Current microbiological pattern and role of respiratory syncytial virus infection in children with acute otitis media in South Jeddah

The Egyptian Journal of Otolaryngology, 2017
Introduction Otitis media is one of the most commonly encountered pediatric ENT diseases. Antibiotic resistance is increasing partly because of their overuse and largely because of changing microbiological strains leading to the disease.
Sherif K. Mohamed, Heba G. Hassan
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The Bacterial Cytoskeleton [PDF]

CBE—Life Sciences Education, 2006
One of the pleasures of teaching introductory biology courses is learning new things about old, familiar subjects … such as the differences between eukaryotes and prokaryotes. For a eukaryotic cell biologist, such learning usually entails examining how bacteria function, in ways other than how they replicate and transcribe DNA and how they synthesize ...
openaire   +2 more sources

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Identification of putative new Escherichia coli flagellar antigens from human origin using serology, PCR-RFlP and DNA sequencing methods

Brazilian Journal of Infectious Diseases
Escherichia coli has been isolated frequently, showing flagellar antigens that are not recognized by any of the 53 antisera, provided by the most important reference center of E.
Monique Ribeiro Tiba, Claúdia de Moura, Marcelo Falsarella Carazzolle, Domingos da Silva Leite   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Review of antimicrobial use and considerations in the elderly population

Clinical Interventions in Aging, 2018
Angela Giarratano,1 Samantha EL Green,1 David P Nicolau2 1Department of Pharmacy, Hartford Hospital, Hartford, CT, USA; 2Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT, USA Abstract: Pharmacologic management of ...
Giarratano A, Green SEL, Nicolau DP
doaj  

A Rare Report of Carbapenem Resistant Vibrio fluvialis Isolated from a case of Walled off Necrosis: A Sequelae of Acute Necrotising Pancreatitis [PDF]

Journal of Clinical and Diagnostic Research
Vibrio fluvialis (V. fluvialis) is commonly found in coastal environments and is an emerging pathogen encountered in diarrhoeal outbreaks and sporadic extraintestinal cases. V.
P Ganesh Perumal, L Venkatakrishnan, B Appalaraju, R Rajakumar, R Someshwaran   +4 more
doaj   +1 more source