Results 81 to 90 of about 393,817 (284)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Comparison of image analysis software packages in the assessment of adhesion of microorganisms to mucosal epithelium using confocal laser scanning microscopy [PDF]

, 2004
We have compared current image analysis software packages in order to find the most useful one for assessing microbial adhesion and inhibition of adhesion to tissue sections.
An, Barthelson, Basset, Borén, Borén, Calderone, Christelle Basset, Clyne, Corkidi, Critchley, Critchley, De Bernardis, Dino Vaira, Elzay, Evans, Falk, Goldhar, Goldstein, Gomez-Suarez, Grivet, Gualtieri, Hood, Ilver, Ivan Roitt, Jansen, John Holton, Mackowiak, Mardh, Millsap, Monod, Montecucco, Ofek, Pernthaler, Pons, Rachel O'Mahony, Reinhard, Robrish, Saitoh, Schonholzer, Sjollema, Sjollema, Stevenson, Sundstrom, Tobin, van Kooten, Watts, Williamson, Wit   +47 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

The Role of Glycans in Bacterial Adhesion to Mucosal Surfaces: How Can Single-Molecule Techniques Advance Our Understanding?

Microorganisms, 2018
Bacterial adhesion is currently the subject of increased interest from the research community, leading to fast progress in our understanding of this complex phenomenon.
Cécile Formosa-Dague, Mickaël Castelain, Hélène Martin-Yken, Karen Dunker, Etienne Dague, Marit Sletmoen   +5 more
doaj   +1 more source

In-situ monitoring of the unstable bacterial adhesion process during wastewater biofilm formation: A comprehensive study

Environment International, 2020
The initial bacterial adhesion phase is a pivotal and unstable step in the formation of biofilms. The initiation of biofilm formation is an unstable process caused by the reversible adhesion of bacteria, which is always time-consuming and yet to be ...
Jinfeng Wang, Qiuju Liu, Deyuan Dong, Haidong Hu, Bing Wu, Hongqiang Ren   +5 more
doaj   +1 more source

Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli [PDF]

, 2011
To avoid detrimental interactions with intestinal microbes, the human epithelium is covered with a protective mucus layer that traps host defence molecules. Microbial properties such as adhesion to mucus further result in a unique mucosal microbiota with
Derde, Melanie, Eeckhaut, Venessa, MacKenzie, Donald A, Marzorati, Massimo, Possemiers, Sam, Roos, Stefaan, Van de Wiele, Tom, Van den Abbeele, Pieter, Van Immerseel, Filip, Vanhoecke, Barbara, Verstraete, Willy   +10 more
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Formation and Dissolution of Bacterial Colonies

, 2015
Many organisms form colonies for a transient period of time to withstand environmental pressure. Bacterial biofilms are a prototypical example of such behavior.
Biais, Nicolas, Lin, Yen Ting, Weber, Christoph, Zaburdaev, Vasily   +3 more
core   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source