Results 121 to 130 of about 12,492,876 (306)

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Substrate Type and Free Ammonia Determine Bacterial Community Structure in Full-Scale Mesophilic Anaerobic Digesters Treating Cattle or Swine Manure

, 2015
The microbial mediated anaerobic digestion (AD) process represents an efficient biological process for the treatment of organic waste along with biogas harvest.
Yan, Zhiying, Yao, Minjie, Zhang, Shiheng, Li, Xiangzhen, Li, Jiabao, Yan, Xuefeng, Wang, Yuanpeng, Rui, Junpeng, Li, XZ (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Key Lab Environm & Appl Microbiol, Beijing 100864, Sichuan, Peoples R China.   +8 more
core   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Nutrition on bacteria by bacterial-feeding nematodes and consequences on the structure of soil bacterial community

, 2006
Bacterial-feeding nematodes are, with protozoa, the main grazers of soil bacteria. Interactions between bacteria and nematodes have important repercussions on soil functioning and particularly on nutrient availability.
Blanc, Cyril, Sy, M., Brauman, A., Villenave, C., Normand, P., Djigal, D.   +5 more
core   +2 more sources

Bacteria associated with moon jellyfish during bloom and post-bloom periods in the Gulf of Trieste (northern Adriatic).

PLoS ONE, 2019
Jellyfish are a prominent component of the plankton community. They frequently form conspicuous blooms which may interfere with different human enterprises.
Maja Kos Kramar, Tinkara Tinta, Davor Lučić, Alenka Malej, Valentina Turk   +4 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

The impact of grassland management regime on the community structure of selected bacterial groups in soils [PDF]

, 2003
The impact of long-term grassland management regimes on microbial community structure in soils was assessed using multivariate analysis of polymerase chain reaction^denaturing gradient gel electrophoresis (PCR^DGGE) banding patterns of selected bacterial
Christopher D. Clegg, Hobbs, P. J., Clegg, C. D., Roger D. L. Lovell, Philip J. Hobbs, Lovell, R. D., C Clegg, Hobbs, Phil   +7 more
core   +1 more source

Sunscreen‐Inspired Nano‐Pesticide for UV‐Shielding and Laccase‐Responsive Delivery of Mancozeb With Enhanced Fungicidal Efficacy and Ecological Safety

Advanced Science, EarlyView.
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan, Xin Ye, Linping He, Cheng Hong, Xu‐Huan Zhao, Gizachew Mulugeta Manahelohe, Xiao‐Tong Feng, Yu‐Cheng Gu, Qiang Bian, Min Wu, Ming‐Zhi Zhang   +10 more
wiley   +1 more source

Community Structure Comparison: Libshuff and Parsimony Statistical Analysis of Colon-Associated Bacterial Populations.

, 2012
Community Structure Comparison: Libshuff and Parsimony Statistical Analysis of Colon-Associated Bacterial Populations.
Philip Smith (188930), Jay Siddharth (188936), Scott J. Parkinson (188984), Natalie Clark (188965), Mark Shaxted (188953), Joanna Jamontt (188971), Nicholas Holway (188947), Devika Sanmugalingam (188979), Ruth Pearson (188941), Matt Butler (188960), Robert P. Watson (124316)   +10 more
core   +1 more source

Impairment of the bacterial biofilm stability by triclosan [PDF]

, 2012
The accumulation of the widely-used antibacterial and antifungal compound triclosan (TCS) in freshwaters raises concerns about the impact of this harmful chemical on the biofilms that are the dominant life style of microorganisms in aquatic systems ...
Hubas, Cedric Roger Rene, Lubarsky, Helen, David M. Paterson (170830), Paterson, David Maxwell, Lubarsky Helen V., Hubas, Cédric, Sebastian Behrens, Helen V. Lubarsky (170802), Paterson, David, Sabine U Gerbersdorf, Cédric Hubas (170814), Paterson David M., Francesco Ricciardi (170821), Francesco Ricciardi, Lubarsky, Helen V., Hubas Cédric, Gerbersdor, Sabine U., Behrens Sebastian, David M Paterson, Cédric Hubas, Ricciardi, Francesco, Paterson, David M., Helen V Lubarsky, Gerbersdorf, Sabine, Gerbersdorf Sabine U., Gerbersdorf, Sabine Ulrike, Ricciardi Francesco, Behrens, Sebastian, Sebastian Behrens (60313), Sabine U. Gerbersdorf (170809), Paterson, David Maxwell; id_orcid   +30 more
core   +1 more source