Results 141 to 150 of about 171,799 (266)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

open access: yesAdvanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang   +11 more
wiley   +1 more source

Bacterial Size Structure as a Method to Analyze Communities

open access: yes, 2019
7th International Symposium on Microbial Ecology, 27 August - 1 September 1995, Santos, São Paulo, Brazil.-- 6 pages, 2 ...
Gasol, Josep M.   +2 more
openaire   +1 more source

The Plant‐to‐Plant Circular Strategy: Coupling Photodegradation and Phytoremediation With Plant‐Based Nanomaterials for Plastic Degradation

open access: yesAdvanced Science, EarlyView.
Plant‐based nanomaterials derived from alfalfa serve as dual‐function catalysts, coupling photodegradation and phytoremediation to degrade polyethylene under UV‐A light and in soil. The nanomaterials work synergistically with alfalfa and soil microbes, achieving efficient plastic breakdown without trophic transfer.
Haoran Liu   +4 more
wiley   +1 more source

Tree diversity shapes soil bacterial community structure under low abiotic heterogeneity in the Atlantic forest. [PDF]

open access: yesArch Microbiol
Tomachewski D   +10 more
europepmc   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

open access: yesAdvanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa   +11 more
wiley   +1 more source

From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology

open access: yesAdvanced Science, EarlyView.
Engineering synthetic microbial consortia requires moving beyond intracellular genetic circuits toward coordinated multicellular design. A modular systems‐engineering framework is presented that integrates communication, temporal coordination, ecological structuring, and predictive modeling to guide application‐dependent consortium design ...
Miguel Fernández‐Niño   +9 more
wiley   +1 more source

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