Results 111 to 120 of about 1,761,029 (289)

Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system

eLife, 2014
Bacteria have to avoid recognition by the host immune system in order to establish a successful infection. Peptidoglycan, the principal constituent of virtually all bacterial surfaces, is a specific molecular signature recognized by dedicated host ...
Magda Luciana Atilano, Pedro Matos Pereira, Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho, Sérgio Raposo Filipe   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Antibacterial effects of lidocaine and saline irrigation on Escherichia coli in superficial surgical wounds

Animal Models and Experimental Medicine
This study evaluated the antibacterial effects of 2% lidocaine and its combination with 0.9% saline solution on Escherichia coli infection in superficial surgical wounds in Wistar rats.
David Ramírez‐Tapia, José A. Ortega‐Salgado, Stephania Rámirez‐Guzmán, Jorge Lopez‐Lopez, Alejandro Rodríguez‐Baéz, Natalia Nuño‐Lámbarri, Eduardo E. Montalvo‐Javé   +6 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Kiwifruit bacterial canker in 'Hayward' kiwifruit : the application of observational study design and epidemiological techniques to the study of disease outbreaks affecting plant health : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Epidemiology, Institute of Veterinary, Animal and Biomedical Sciences at Massey University, Manawatu, New Zealand [PDF]

, 2017
Bacterial canker of kiwifruit, caused by Pseudomonas syringae pv. actinidiae (Psa) biovar 3, was first recorded in New Zealand in November 2010 and quickly made production of the goldfleshed kiwifruit cultivar, ‘Hort16A’, which is highly susceptible to
Froud, Karyn Janine
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Development and Implementation of a Single Radial Diffusion Technique for Quality Control of Acellular Pertussis Vaccines

Vaccines
Background/Objectives: An assay for protein content is essential but insufficient for quality control of acellular pertussis vaccines, which might consist of up to five components, each needing individual quantification.
Chongyang Wu, Xi Wang, Yu Zhou, Xinshuo Zhu, Yu Ma, Wenming Wei, Yuntao Zhang   +6 more
doaj   +1 more source

Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine

mBio, 2018
Bivalent rLP2086 (Trumenba), a vaccine for prevention of Neisseria meningitidis serogroup B (NmB) disease, was licensed for use in adolescents and young adults after it was demonstrated that it elicits antibodies that initiate complement-mediated killing
Lisa K. McNeil, Robert G. K. Donald, Alexey Gribenko, Roger French, Nathaniel Lambert, Shannon L. Harris, Thomas R. Jones, Sheng Li, Gary Zlotnick, Ulrich Vogel, Heike Claus, Raquel Abad, Julio A. Vazquez, Ray Borrow, Jamie Findlow, Muhamed-Kheir Taha, Ala-Eddine Deghmane, Dominique A. Caugant, Paula Kriz, Martin Musilek, Xin Wang, Jeni Vuong, Leonard W. Mayer, Michael W. Pride, Kathrin U. Jansen, Annaliesa S. Anderson   +25 more
doaj   +1 more source

Bacterial signals promote mosquito development [PDF]

Science, 2017
Microbiota The ways of the microbiota are many and mysterious. All organisms have prokaryote partners that contribute to health, as well as disease. Coon et al. report that larval mosquitos require bacteria in their gut to complete development into an adult insect. In this case, the bacteria are not making a nutritional contribution, however.
openaire   +1 more source