Results 91 to 100 of about 11,136,295 (320)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Spontaneous Bacterial Peritonitis in an Adult Patient with Minimal Change Disease

, 2021
In Hee Lee, Hong Ik Kim, Min-Kyung Kim, Dong Jik Ahn   +3 more
openalex   +1 more source

1213. A TRAIL/IP-10/CRP Signature Distinguishes between Viral and Bacterial Infection in Chronic Obstructive Pulmonary Disease Patients [PDF]

, 2020
Meital Paz, Salim Halabi, Shachaf Shiber, Ami Neuberger, Neta Petersiel, Mordechai Grupper, Dani Kirshner, Noa Avni, Michal Stein, Gali Kronenfeld, Liran Shani, Tanya Gottlieb, Ynon Lishtzinsky, ‪Yasmin Maor‬‏, Shirly Yanai, Kfir Oved, Eran Eden, Michael J. Drescher, Michal Paul   +18 more
openalex   +1 more source

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

Nature Communications, 2015
Asthma is prevalent in Western countries, and recent explanations have evoked the actions of the gut microbiota. Here we show that feeding mice a high-fibre diet yields a distinctive gut microbiota, which increases the levels of the short-chain fatty ...
A. Thorburn, Craig I. McKenzie, S. Shen, D. Stanley, L. Macia, L. Mason, Laura K. Roberts, Connie H. Y. Wong, Raymond Shim, R. Robert, N. Chevalier, Jian Tan, Eliana Mariño, R. Moore, Lee H Wong, M. McConville, D. Tull, L. Wood, V. Murphy, J. Mattes, P. Gibson, C. Mackay   +21 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Microbiome and metabolic disease: revisiting the bacterial phylum Bacteroidetes

Journal of molecular medicine, 2016
Bacterial species composition in the gut has emerged as an important factor in obesity and its related metabolic diseases such as type 2 diabetes. Out of thousands of bacterial species-level phylotypes inhabiting the human gut, the majority belong to two
E. Johnson, S. Heaver, William Walters, R. Ley   +3 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Isolation and identification of pathogens of Morchella sextelata bacterial disease. [PDF]

Front Microbiol, 2023
Zhu X, Ma K, Sun M, Zhang J, Liu L, Niu S.   +5 more
europepmc   +1 more source