Results 71 to 80 of about 1,050,726 (302)

Foodborne disease surveillance annual summary 1979 [PDF]

open access: yes
In 1979 there were 460 outbreaks (13,207 cases) of foodborne disease reported to the Centers for Disease Control. The etiology was confirmed in 37% of outbreaks.

core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Foodborne disease surveillance annual summary 1981 [PDF]

open access: yes
In 1981 there were 568 outbreaks (14,432 cases) of foodborne disease reported to the Centers for Disease Control. The etiology was confirmed in 44% of the outbreaks. Bacterial pathogens accounted for 185 outbreaks (8,208 cases).

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Meningococcal Antigen Typing System (MATS)-Based Neisseria meningitidis Serogroup B Coverage Prediction for the MenB-4C Vaccine in the United States

open access: yesmSphere, 2017
Neisseria meningitidis is the most common cause of bacterial meningitis in children and young adults worldwide. A 4-component vaccine against N. meningitidis serogroup B (MenB) disease (MenB-4C [Bexsero]; GSK) combining factor H binding protein (fHBP ...
Gowrisankar Rajam   +7 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Foodborne disease surveillance annual summary 1980 [PDF]

open access: yes
In 1980 there were 612 outbreaks (13,791 cases) of foodborne disease reported to the Centers for Disease Control. In 36% of the outbreaks, the etiology was confirmed. Bacterial pathogens accounted for 136 outbreaks (6,891 cases).

core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Streptococcus pneumoniae, 2021 [PDF]

open access: yes
Citation: Centers for Disease Control and Prevention. 2021. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2021.www.cdc.gov/abcs/downloads/SPN_Surveillance_Report_2021.pdfDataset version: May ...

core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The characterisation of polymicrobial bacterial communities in the lower respiratory tract of individuals with chronic pulmonary disease [PDF]

open access: yes
Microbial diversity encompasses the whole of the Earth’s biosphere and is incredibly vast. The microbial diversity of three disparate micro-environments using two culture-independent techniques (denaturing gradient gel electrophoresis (DGGE) and 454 ...
Purcell, Paul
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