Results 81 to 90 of about 363,402 (264)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Selective Pressure of Heavy Metals on Soil Microbial Taxa near a Smelting Area

Toxics
Soil pollution by heavy metals (HMs) poses a major threat to soil quality and human health, with mining and smelting industries identified as key sources.
Radina Nikolova, Evan Gatev, Anelia Kenarova, Michaella Petkova, Nikolai Dinev, Petr Baldrian, Galina Radeva   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Bacterial Diversity in Al-Asfar Lake, Al Ahsa Oasis, Saudi Arabia

Journal of Pure and Applied Microbiology
This study aimed to investigate bacterial diversity in Al-Asfar Lake, Al Ahsa Oasis, Saudi Arabia, based on a polyphasic approach. Water samples were collected and divided into two parts.
Abeer Al Mousa, Munirah Aldayel, Marwa A.M. Genena, Zeinab A. El-Moaty, Ashraf Khalifa   +4 more
doaj   +1 more source

Salicylic Acid and Jasmonic Acid Signaling Defense Pathways Reduce Natural Bacterial Diversity on Arabidopsis thaliana

Molecular Plant-Microbe Interactions, 2007
Terrestrial plants serve as large and diverse habitats for a wide range of pathogenic and nonpathogenic microbes, yet these communities are not well described and little is known about the effects of plant defense on microbial communities in nature.
Joel M. Kniskern, M. Brian Traw, Joy Bergelson   +2 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Beyond one-size-fits-all approach: How do various harvesting strategies shape soil microbial diversity in Larix gmelinii (Daxinganling larch) forests of the Greater Khingan Mountains?

Frontiers in Microbiology
This study analyzed the effects of six harvesting strategies, including primary forests (PF), shelterwood cutting (SC), clear cutting (CC), optional cutting with low intensity (OCL), optional cutting with moderate intensity (OCM), and optional cutting ...
Yufeng Wang, Yufeng Wang, Na Ta, Na Ta, Hao Zhang, Hao Zhang, Min Li, Min Li, Shengwei Liu, Shengwei Liu, Jiaxing Gong, Jiaxing Gong, Yake Song, Rula Sa   +13 more
doaj   +1 more source

Bacterial diversity in antibiotic wastewater treatment

Water Science and Technology, 2013
The bacterial diversity of an antibiotic industrial wastewater treatment system was analyzed to provide the information required for further optimization of this process and for identification of bacterial strains that perform improved degradation of antibiotic industrial wastewater.
J, Han, L Y, Wang, B Y, Cai
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Fungi contribute more than bacteria to the ecological uniqueness of soil microbial communities in alpine meadows

Global Ecology and Conservation
Understanding the ecological uniqueness of soil bacterial and fungal communities and their driving factors can provide more targeted protection for soil microbial diversity.
Jie Li, Huan Yang, Yuan Yuan Duan, Xiao Dan Sun, Xiao Pan Pang, Zheng Gang Guo   +5 more
doaj   +1 more source