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Comparing Bacterial DNA Microarray Fingerprints

Statistical Applications in Genetics and Molecular Biology, 2005
Epidemiologic and forensic investigations often require assays to detect subtle genetic differences between closely related microorganisms. Typically, gel electrophoresis is used to compare randomly amplified DNA fragments between microbial samples, where the patterns of DNA fragment sizes are viewed as genotype ‘fingerprints’.
Willse, Alan   +5 more
openaire   +3 more sources

Bacterial Infection Promotes DNA Hypermethylation

Journal of Dental Research, 2007
Maternal oral infection, caused by bacteria such as C. rectus or P. gingivalis, has been implicated as a potential source of placental and fetal infection and inflammatory challenge, which increases the relative risk for pre-term delivery and growth restriction.
Y A, Bobetsis   +8 more
openaire   +2 more sources

Characterization of the bacterial microbiome in first‐pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

Letters in Applied Microbiology, 2019
Numerous studies have reported bacterial DNA in first‐pass meconium samples, suggesting that the human gut microbiome is seeded prior to birth. However, these studies have not been able to discriminate between DNA from living bacterial cells, DNA from ...
L. Stinson, J. Keelan, Matthew S. Payne
semanticscholar   +1 more source

DNA transfer in bacterial conjugation

Journal of Molecular Biology, 1966
Chromosome transfer from Hfr to F − cells was analyzed by labeling the DNA of the Hfr cells with [ 3 H]thymine prior to mating, and/or by labeling any DNA made during mating. The F − cells were either starved of adenine or heavily irradiated with ultraviolet light, with the aim of preventing them from synthesizing DNA.
J D, Gross, L G, Caro
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Arrest of Bacterial DNA Replication

Annual Review of Microbiology, 1992
The chromosomes of both gram-positive and gram-negative bacteria contain sites that arrest the progression of DNA replication forks. These replication-arrest sites limit the end of the replication cycle to a particular region of the chromosome, called the terminus region.
openaire   +2 more sources

Bacterial CpG-DNA Licenses TLR9

2002
The family of Toll-like receptors (TLRs) plays an important role in the innate immune response to pathogens. TLRs sense pathogen associated molecular patterns (PAMP) and lead to the stimulation of immune cells. In man, so far ten members (TLR1-10) have been reported.
S, Bauer, H, Wagner
openaire   +2 more sources

Bacterial DNA in Clarkia fossils

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1991
For the growing number of investigators who study ancient DNA, the most stimulating paper published during 1990 reported the determination of a chloroplast DNA sequence from a plant compression fossil found in a Miocene deposit at Clarkia, Idaho (Golenberg et al. 1990). During August 1990, S.P.
Sidow, A.   +2 more
openaire   +3 more sources

DNA uptake during bacterial transformation

Nature Reviews Microbiology, 2004
Naturally competent bacteria are able to take up exogenous DNA and undergo genetic transformation. The transport of DNA from the extracellular milieu into the cytoplasm is a complex process, and requires proteins that are related to those involved in the assembly of type IV pili and type II secretion systems, as well as a DNA translocase complex at the
Inês, Chen, David, Dubnau
openaire   +2 more sources

Untangling bacterial DNA topoisomerases functions

Biochemical Society Transactions
Topoisomerases are the main enzymes capable of resolving the topological constraints imposed by DNA transactions such as transcription or replication. All bacteria possess topoisomerases of different types. Although bacteria with circular replicons should encounter similar DNA topology issues, the distribution of topoisomerases varies from one ...
Céline Borde   +2 more
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Preparation of Bacterial Plasmid DNA

Current Protocols in Neuroscience, 1998
AbstractThe protocols in this unit describe methods for preparing bacterial plasmid DNA free from chromosomal DNA. The first is an alkaline lysis miniprep suitable for screening a moderate number of bacterial colonies by restriction endonuclease cleavage and agarose gel electrophoresis.
J, Engebrecht, J S, Heilig, R, Brent
openaire   +3 more sources

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