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Bacterial DNA Methylation and Methylomes
2016Formation of C5-methylcytosine, N4-methylcytosine, and N6-methyladenine in bacterial genomes is postreplicative and involves transfer of a methyl group from S-adenosyl-methionine to a base embedded in a specific DNA sequence context. Most bacterial DNA methyltransferases belong to restriction-modification systems; in addition, "solitary" or "orphan ...
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Mechanisms of immune stimulation by bacterial DNA [PDF]
Bacterial DNA promotes powerful immune system activation because of its content of characteristic sequence motifs. These sequences induce cellular changes that promote inflammation and the generation of Thl responses. This activation involves internalization of DNA as well as the activation of NF-κB and stress kinases.
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Hybridization of Bacterial DNA on Filters
Cold Spring Harbor Protocols, 2006David W. Russell, Joseph Sambrook
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