Results 341 to 350 of about 4,174,904 (387)

ROLE OF PEROXYNITRITE IN THE PROTEIN OXIDATION AND APOPTOTIC DNA FRAGMENTATION IN VASCULAR SMOOTH MUSCLE CELLS STIMULATED WITH BACTERIAL LIPOPOLYSACCHARIDE AND INTERFERON-γ

, 1997
Michael O’Connor, Andrew L. Salzman, Csaba Szabó   +2 more
openalex   +1 more source

Is bacterial DNA a surrogate marker of bacterial translocation in cirrhosis?

Journal of Hepatology, 2008
openaire   +2 more sources

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

From Shadows to Spotlight: Enhancing Bacterial DNA Detection in Blood Samples through Cutting-Edge Molecular Pre-Amplification. [PDF]

Antibiotics (Basel)
Reinicke M, Braun SD, Diezel C, Lemuth O, Engelmann I, Liebe T, Ehricht R.   +6 more
europepmc   +1 more source

Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control

Advanced Science, EarlyView.
Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui, Wonjoon Moon, Pu‐Ting Dong, Carolina dos Anjos, Laisa Negri, Hao Yan, Ying Wang, Joshua Tam, Tianhong Dai, R. Rox Anderson, Jeremy Goverman, Jeffrey A. Gelfand, Seok‐Hyun Yun   +12 more
wiley   +1 more source

A method for isolation of plasmid DNA replication intermediates from unsynchronized bacterial cultures for electron microscopy analysis.

, 1998
S Srutkowska, Grażyna Konopa, Grzegorz Węgrzyn   +2 more
openalex   +2 more sources

Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection. [PDF]

Front Immunol
Marinho FV, Brito C, de Araujo ACVSC, Oliveira SC.   +3 more
europepmc   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

Advanced Science, EarlyView.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu, Xin Dong, Hao Zhou, Ze‐Yan Li, Bo Wang, Ya‐Ping Song, Zhi‐Bing Liu, Xue Lu, Yi‐Hao Zhang, Yichao Huang, Hua Wang, De‐Xiang Xu   +11 more
wiley   +1 more source

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

Advanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu, Yujing Song, Tao Dong, Wenlu Ouyang, Chao Quan, Liujiazi Shao, Leonard Barasa, Paul R. Thompson, Mao Zhang, Jianjie Ma, Katsuo Kurabayashi, Yongqing Li   +11 more
wiley   +1 more source

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source