Results 41 to 50 of about 604,900 (351)

In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL

Antibiotics, 2022
MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress.
Robin Wray, Paul Blount, Junmei Wang, Irene Iscla   +3 more
doaj   +1 more source

Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]

, 2018
This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau, Ivanova, Kristina Dimitrova, Ramon Portés, Eva, Tzanov, Tzanko   +3 more
core   +2 more sources

Antimicrobial Resistance in Commensal Flora of Pig Farmers

Emerging Infectious Diseases, 2004
We assessed the quantitative contribution of pig farming to antimicrobial resistance in the commensal flora of pig farmers by comparing 113 healthy pig farmers from the major French porcine production areas to 113 nonfarmers, each matched for sex, age ...
Hélène Aubry-Damon, Karine Grenet, Penda Sall-Ndiaye, Didier Che, Eugenio Cordeiro, Marie-Elisabeth Bougnoux, Emma Rigaud, Yann Le Strat, Véronique Lemanissier, Laurence Armand-Lefèvre, Didier Delzescaux, Jean-Claude Desenclos, Michel Liénard, Antoine Andremont   +13 more
doaj   +1 more source

Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]

, 2005
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
A Alvarez, DJ McCaig, DT Bearden, EH Ibrahim, EM Brown, European Antimicrobial Resistance Surveillance System, Flora M. Haaijer-Ruskamp, GL Mandell, IC Gyssens, IM Gould, J Avorn, J Cobo, J Gans de, J Hatton, JG Bartlett, John E. Degener, JW Warren, Marian Laseur, ME Kasteren van, ME Kasteren van, Peter G. M. Mol, Petra Denig, PGM Mol, PGM Mol, PGM Mol, PP Cook, Prashant V. NannanPanday, R Grol, Rijk O. B. Gans, RJ Meyer, RP Wenzel, SE Buijk, SJ Atlas, SL Bronzwaer, W Kasje, WA Knaus, WE Stamm   +36 more
core   +3 more sources

Whole-genome sequencing targets drug-resistant bacterial infections [PDF]

Human Genomics, 2015
During the past two decades, the technological progress of whole-genome sequencing (WGS) had changed the fields of Environmental Microbiology and Biotechnology, and, currently, is changing the underlying principles, approaches, and fundamentals of Public Health, Epidemiology, Health Economics, and national productivity.
N. V. Punina, N. M. Makridakis, M. A. Remnev, A. F. Topunov   +3 more
openaire   +2 more sources

Antimicrobial peptides for combating drug-resistant bacterial infections

Drug Resistance Updates, 2023
The problem of drug resistance due to long-term use of antibiotics has been a concern for years. As this problem grows worse, infections caused by multiple bacteria are expanding rapidly and are extremely detrimental to human health. Antimicrobial peptides (AMPs) are a good alternative to current antimicrobials with potent antimicrobial activity and ...
Jiaqi Xuan, Weiguo Feng, Jiaye Wang, Ruichen Wang, Bowen Zhang, Letao Bo, Zhe-Sheng Chen, Hui Yang, Leming Sun   +8 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Antimicrobial Resistance in Human and Animal Pathogens in Zambia, Democratic Republic of Congo, Mozambique and Tanzania: An Urgent Need of a Sustainable Surveillance System. [PDF]

, 2013
A review of the published and unpublished literature on bacterial resistance in human and animals was performed. Sixty-eight articles/reports from the Democratic Republic of Congo (DRC), Mozambique, Tanzania and Zambia were reviewed.
Matee, Mecky, Mshana, Stephen E, Rweyemamu, Mark   +2 more
core   +1 more source

The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. [PDF]

, 2020
HT61 is a small quinolone-derived compound previously demonstrated to exhibit bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). When
Amison, RT, Bruce, KD, Coates, A, Faure, M-E, Hu, Y, O'Shaughnessy, BG, Page, CP   +6 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source