Results 41 to 50 of about 52,215 (235)

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source

Efficacy of Essential Oil of Algrizea minor Sobral, Faria & Proença (Myrtaceae) in Combating Methicillin‐resistant Staphylococcus aureus: Antibacterial and Virulence Modulation Studies Conducted In Vitro and In Vivo

Chemistry &Biodiversity, EarlyView.
This study explored the antibacterial, antivirulence, and in vivo effects of Algrizea minor essential oil (EOAM), against MRSA isolates. Chemical analysis by GC‐MS has been performed. The oil exhibited synergistic effects when combined with amoxicillin and oxacillin, inhibiting biofilm formation and reducing S. aureus‐induced hemolysis.
Amanda Vieira de Barros, Bruno Oliveira de Veras, Henrique Nelson Pereira Costa Júnior, Raudiney Frankilin Vasconcelos Mendes, Patryck Érmerson Monteiro dos Santos, Jael Fernandes Tavares, Daniela Maria do Amaral Ferraz Navarro, Rafael Matos Ximenes, Patrícia Maria Guedes Paiva, Clovis Macedo Bezerra Filho, Josinaldo Alves da Silva, Márcia Vanusa da Silva, João Paulo Martins de Lima, Henrique Douglas Melo Coutinho, Maria Betânia Melo de Oliveira   +14 more
wiley   +1 more source

Bifidobacterium longum subsp. longum CCFM1375 Mitigates Chronic Kidney Disease Progression via Gut Microbiota Modulation and Gut Barrier Restoration

Food Frontiers, EarlyView.
(1) Bifidobacterium longum subsp. longum CCFM1375 restored gut barrier integrity by upregulating ZO‐1/ZO‐2 and suppressing IL‐6/TNF‐α, thereby reducing serum LPS and improving creatinine/BUN levels. (2) Reshaped gut microbiota: enriched beneficial species (Faecalibaculum rodentium, Asaccharobacter celatus, Adlercreutzia equolifaciens) while suppressing
Hongchao Wang, Xinchen Lv, Yue Zhang, Jinlin Zhu, Jia Hua, Bin Liu, Jianxin Zhao, Hao Zhang, Wei Chen, Wenwei Lu, Zhijian Zhang, Liang Wang   +11 more
wiley   +1 more source

PET-scan in diagnosis of non-bacterial thrombotic endocarditis: a case report

The Egyptian Heart Journal
Background Non-bacterial thrombotic endocarditis (NBTE), also known as marantic endocarditis or Libman–Sacks endocarditis, is a rare non-infectious condition affecting mostly the left-sided heart valves of patients who, most often, suffer from ...
Konstantinos Papakonstantinou, Filippos-Paschalis Rorris, Nikoleta Stanitsa, John Kokotsakis   +3 more
doaj   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

Case Report: Heart Transplantation for Refractory Candida tropicalis Endocarditis: A Case Report and Literature Review

Microorganisms
Candida infective endocarditis presents therapeutic challenges with high mortality. A complex case of Candida prosthetic valve endocarditis refractory to standard antifungals (anidulafungin and fluconazole) and high-dose caspofungin was successfully ...
Ricardo El Nouwar, Eva Larranaga Lapique, Frédéric Vanden Eynden, Delphine Martiny, Myriam Remmelink, Ana Roussoulières, Maya Hites   +6 more
doaj   +1 more source

Secondary lung abscess caused by an esophagorespiratory fistula in a patient with a past history of heavy alcohol consumption

Journal of General and Family Medicine, EarlyView.
This case highlights the importance of considering malignancy‐related esophagorespiratory fistulas in patients with presumed aspiration‐related lung abscesses and heavy alcohol use. Abstract A man in his 60s was ultimately diagnosed with a secondary lung abscess caused by an esophagorespiratory fistula.
Shuhei Nozaki, Taku Yabuki, Taro Shimizu
wiley   +1 more source

Colon Cancer with Streptococcus gallolyticus Aortic Valve Endocarditis: A Missing Link?

Case Reports in Gastrointestinal Medicine, 2019
Bacterial endocarditis is commonly encountered in clinical practice. Many bacterial species have been implicated; however, Streptococcus gallolyticus species (formerly “bovis”) has driven attention given a historical association with colon cancer ...
Chukwunonso Chime, Harish Patel, Kishore Kumar, Ahmed Elwan, Manoj Bhandari, Ariyo Ihimoyan   +5 more
doaj   +1 more source

Dose‐dependent association of systemic comorbidities with periodontitis severity: A large population cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background To examine whether the associations between periodontitis and multiple systemic conditions increase with increasing severity of periodontitis using a multi‐center electronic health record (EHR) repository. Methods A cross‐sectional analysis was conducted using EHR data from 9 dental schools in the United States.
Muhammad H. A. Saleh, Hamoun Sabri
wiley   +1 more source

A Case Report of Tricuspid Valve Endocarditis in a 15-month-old Child Following COVID-19 Infection

Research in Cardiovascular Medicine
The novel SARS-CoV-2 virus, also known as COVID-19, has started a global pandemic since late December 2019. The infection is primarily manifested with fever, coughing, and myalgia, and in more severe cases causes acute respiratory distress syndrome ...
Maryam Ghadimi, Rasool Ferasatkish, Nader Givtaj, Nahid Aghdaei, Yasmin Chaibakhsh   +4 more
doaj   +1 more source