Results 201 to 210 of about 920,931 (266)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Chemotherapy of bacterial infection.

Nihon Naika Gakkai Zasshi, 1994
openaire   +3 more sources

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

A Bacterial Effector Hijacks NBR1 to Modulate Both Autophagy and Ubiquitination-Mediated Degradation That Promotes Bacterial Infection. [PDF]

Plant Biotechnol J
Shi Y, Fang F, Cui X, Shi H, Yang Z, Li X, Zhou C, Wang X.   +7 more
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Role of necroptosis in pulpitis: integration of bacterial infection, immune imbalance, and oxidative stress. [PDF]

PeerJ
Wang X, Wang Y, Pang Z, Gong P, Ma X, Qiu Y, Li J, Peng L, Liu Z.   +8 more
europepmc   +1 more source

A neuroimmune pathway drives bacterial infection. [PDF]

Sci Adv
Wang N, Liu J, Wu R, Chen F, Zhang R, Yu C, Zeh H, Xiao X, Wang H, Billiar TR, Zeng L, Jiang J, Tang D, Kang R.   +13 more
europepmc   +1 more source

The battle between bacterial infection and autophagy in aquatic animals. [PDF]

Front Immunol
Wang Q, Xu H, Jin J, Yang Y, Jänsch L, Li S.   +5 more
europepmc   +1 more source

Visualization of multidrug-resistant bacterial infection trends in the intensive care units. [PDF]

PLoS One
Jeon W, Lee YM, Kim DY, Park KH, Lee MS.
europepmc   +1 more source