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Current Opinion in Gastroenterology, 2011
We review here new developments in chronic hepatitis B (CHB) treatment, based on review of published articles between December 2009 and November 2010.It is estimated that two-thirds of US CHB patients have not been identified, evaluated and appropriately treated, largely due to lack of knowledge and awareness of CHB among medical professionals and at ...
Hejun, Yuan, William M, Lee
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We review here new developments in chronic hepatitis B (CHB) treatment, based on review of published articles between December 2009 and November 2010.It is estimated that two-thirds of US CHB patients have not been identified, evaluated and appropriately treated, largely due to lack of knowledge and awareness of CHB among medical professionals and at ...
Hejun, Yuan, William M, Lee
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Annals of Internal Medicine, 1988
Excerpt To the Editor:Perrillo and colleagues (1) make an important contribution to the study of chronic hepatitis B treatment.
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Excerpt To the Editor:Perrillo and colleagues (1) make an important contribution to the study of chronic hepatitis B treatment.
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Management of Chronic Hepatitis B
European Journal of Gastroenterology & Hepatology, 2011Chronic hepatitis B affects 400 million people worldwide. The criteria for initiating and stopping treatment are still under debate in spite of well-established agents for its treatment.
Lai, CL, Yuen, MF
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Treatment of chronic hepatitis B
The Lancet Infectious Diseases, 2001This review updates the treatment of chronic hepatitis B infection. Complete eradication of hepatitis B virus (HBV) is not possible, so the efficacy of treatment has to be assessed by whether it can limit long-term cirrhosis-related complications. We discuss two major groups of treatments--immunomodulators (interferon alfa, thymosin alpha1, therapeutic
Lai, CL, Yuen, MF
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Pathology of Chronic Hepatitis B and Chronic Hepatitis C
Clinics in Liver Disease, 2010Histologic evaluation of the liver is a major component in the medical management and treatment algorithm of patients with chronic hepatitis B (HBV) and chronic hepatitis C (HCV). Liver biopsy in these patients remains the gold standard, and decisions on treatment are often predicated on the degree of damage and stage of fibrosis. This article outlines
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Treatment of Chronic Hepatitis B
Current Pharmaceutical Design, 2002Infection with the hepatitis B virus has switched over the last 20 years from the classical HBeAg positive serologic pattern to a HBeAg negative form that is linked, in the Mediterranean basin, with the epidemiologic replacement of the causative wild-type of virus B with mutant variants, whereby mutations in the core-promoter and in the pre-core region
M, Lagget, M, Rizzetto
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Treatment of chronic hepatitis B
Journal of Viral Hepatitis, 1994SUMMARY.Chronic infection with the hepatitis B virus (HBV) is a major cause of worldwide morbidity and mortality. A large number of therapeutic approaches has been tried, including interferon (IFN), nucleoside analogues and immunomodulators. To date controlled clinical trials have shown that only IFN is of long‐term value but many patients fail to ...
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Clinics in Liver Disease, 2012
The management of chronic hepatitis B virus (HBV) infection requires understanding the natural history of the disease as well as the risks, benefits, and limitations of the therapeutic options. This article covers the principles governing when to start antiviral therapy, discusses recent advances using hepatitis B surface antigen quantification to ...
Alexander, Kuo, Robert, Gish
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The management of chronic hepatitis B virus (HBV) infection requires understanding the natural history of the disease as well as the risks, benefits, and limitations of the therapeutic options. This article covers the principles governing when to start antiviral therapy, discusses recent advances using hepatitis B surface antigen quantification to ...
Alexander, Kuo, Robert, Gish
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Management of chronic hepatitis B
Gastroenterology Clinics of North America, 2004Chronic hepatitis B (CHB) is a major worldwide cause of chronic liver disease and a significant public health issue. Three predominant clinical presentations are recognized: hepatitis B e antigen(HBeAg) or typical CHB, HBeAg-negative or atypical CHB, and inactive CHB.
Marc G, Ghany, Edward C, Doo
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Treatment of Chronic Hepatitis B
Minerva gastroenterologica e dietologica, 2010Approximately 350-420 million people worldwide are chronically infected with hepatitis B virus (HBV). Chronic hepatitis B can result in liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Reactivation of hepatitis B is possible in patients with inactive or resolved hepatitis B often leading to liver failure.
Lai, CL, Yuen, RMF
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