Hepatitis B core-related antigen as a multifaceted biomarker in chronic hepatitis B: implications for immune activity and hepatocellular carcinoma prediction [PDF]
Background/Aims Hepatitis B core-related antigen (HBcrAg) reflects both serum hepatitis B virus (HBV) DNA and intra-hepatic covalently closed circular DNA activity, offering potential advantages over conventional biomarkers in monitoring chronic ...
Kwon Yong Tak +2 more
doaj +2 more sources
Advancing Global Hepatitis B Elimination: The Case for Using Maize as a Low-Cost, Heat-Stable, and Scalable Oral Vaccine [PDF]
Because hepatitis B virus (HBV) remains a major global health burden, innovative strategies are essential to achieve the World Health Organization’s goal of eliminating viral hepatitis and closing persistent coverage gaps for injectable vaccines.
Muneaki Watanabe, John A. Howard
doaj +2 more sources
Correlation between serum quantitative HBsAg and HBV DNA levels in chronic hepatitis B patients [PDF]
Background/Aim. Quantitative hepatitis B virus (HBV) surface antigen (qHBsAg) has become increasingly wide-spread in the last few years in both diagnostic and therapeutic protocols for HBV infection.
Pete Maria +5 more
doaj +1 more source
Background: To evaluate the protective efficacy of a hepatitis B (HB) vaccination program in Taiwan among high-risk children. Methods: Children born to HBeAg-positive mothers from 2001 to 2010 were invited back.
Chen-Hsuan Wu +3 more
doaj +1 more source
Correction for Suzuki et al., “Evaluation of fully automated chemiluminescent enzyme immunoassays for hepatitis B core-related antigen components, phosphorylated and non-phosphorylated hepatitis B core antigens: clinical significance and dynamics during hepatitis B e antigen seroconversion” [PDF]
Takanori Suzuki +10 more
doaj +2 more sources
Hepatitis B e antigen-negative chronic hepatitis B [PDF]
Summary HBeAg-negative CHB has now a worldwide distribution, developing in the course of HBeAg-positive chronic HBV infection during or after the phase of HBeAg loss and its seroconversion to anti-HBe. It is caused by replicating noncytopathic HBV mutants either unable to produce HBeAg (precore mutants) or with down-regulated transcription of the ...
Hadziyannis, SJ, Vassilopoulos, D
openaire +3 more sources
The predictive effect of quantitative anti-hepatitis B core on double-negative HBV DNA and RNA remains unstudied. We observed dynamic changes in this measure in chronic hepatitis B patients receiving entecavir for 10 years, evaluating its predictive ...
Xi Zhang +8 more
doaj +1 more source
Characterization and evaluation of liver fibrosis grade in patients with chronic hepatitis B virus infection and normal transaminases [PDF]
Background/Aims The objective of our study was to determine the epidemiological, laboratory, and serological characteristics of patients with chronic hepatitis B virus (HBV) infection and normal transaminases.
San Juan López Cristina +6 more
doaj +1 more source
Objective Use of dried blood spots (DBS) for detection of hepatitis B virus (HBV) markers of infection has the potential to facilitate diagnosis of HBV infection especially in resource-limited countries.
Minami Kikuchi +5 more
doaj +1 more source
Point-of-Care Testing for Hepatitis Viruses: A Growing Need
Viral hepatitis, caused by hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis D virus (HDV), or hepatitis E virus (HEV), is a major global public health problem.
Matthew D. Pauly, Lilia Ganova-Raeva
doaj +1 more source

