Results 31 to 40 of about 70,254 (168)

Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial). [PDF]

open access: yesPLoS ONE, 2018
CONTEXT:Current drugs for chronic hepatitis B therapy have a poor efficacy in terms of post-treatment sustained viral suppression and generate important side effects during and after therapy.
Mamun Al Mahtab   +8 more
doaj   +1 more source

Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B

open access: yesViruses, 2021
As current interventions for chronic hepatitis B (CHB) rarely induce cure, more effective drugs are needed. Short-term treatment of woodchucks with the novel immunomodulator AIC649, a parapoxvirus-based stimulator of toll-like receptor 9 dependent and ...
Kyle E. Korolowicz   +8 more
doaj   +1 more source

T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model

open access: yesActa Pharmaceutica Sinica B, 2017
Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV) in vitro, limited research has been done with this drug in vivo.
Xiuxiu Sang   +14 more
doaj   +1 more source

Hepatitis B e antigen-negative chronic hepatitis b in Hong Kong [PDF]

open access: yesHepatology, 2000
Hepatitis B e antigen-negative chronic hepatitis B (e−CHB) has been reported in Asia but its prevalence and clinical significance have not been determined. The aims of this study were to determine the prevalence of e−CHB in Hong Kong and the frequency of precore and core promoter mutations in these patients.
Chan, Henry L. Y.   +4 more
openaire   +3 more sources

Hepatitis B e Antigen–Negative Chronic Hepatitis B

open access: yesTAJ: Journal of Teachers Association, 2018
Abstract not availableTAJ 2012; 25: 90 ...
DK Mohanta   +8 more
openaire   +2 more sources

Serum hepatitis B core-related antigen as a surrogate marker of hepatitis B e antigen seroconversion in chronic hepatitis B

open access: yesWorld Journal of Gastroenterology, 2021
Quantitative hepatitis B core-related antigen (qHBcrAg) has a better correlation with intrahepatic hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) than HBV DNA or hepatitis B e antigen (HBeAg), but data are still lacking for its clinical application.The aim was to investigate serum qHBcrAg levels in patients with chronic hepatitis B and
Chi, Xiu-Mei   +7 more
openaire   +2 more sources

Hepatitis B seroconversion revisited: new insights into the natural history of acute hepatitis B virus (HBV) infection from quantitative and highly sensitive assays and novel biomarkers

open access: yesVirology Journal, 2021
Background Hepatitis B virus (HBV) serum markers during typical acute self-limited infection are usually depicted as a composite of traditional HBV markers.
Mary C. Kuhns   +4 more
doaj   +1 more source

Viral Determinants of Hepatitis B Surface Antigen Seroclearance in Hepatitis B e Antigen–Negative Chronic Hepatitis B Patients [PDF]

open access: yesThe Journal of Infectious Diseases, 2011
We studied whether quantification of serum HBsAg and HBV DNA levels could predict spontaneous HBsAg clearance in patients with negative hepatitis B e antigen (HBeAg).Serum HBsAg and HBV DNA levels were measured at baseline among a longitudinal cohort of 103 HBeAg-negative patients recruited since 1997.Twelve (12%) patients developed HBsAg seroclearance
Henry Lik-Yuen, Chan   +4 more
openaire   +2 more sources

THE STATE OF CELL MEDIATED IMMUNITY AMONG HEPATITIS B SURFACE ,ANTGENI CARRIERS IN IRAN, [PDF]

open access: yesActa Medica Iranica, 1987
Cell-mediated immune (CMI) s t a t us and sub- popul at i ons o f pe r ipheral b l ood lymphocytes were investigated in one hundre d volunt a ry blood donors who were car r ier s of Ag • HE S A signi f i c ant decr e ase of t otal T-cells ...
A. MASSOUD
doaj   +2 more sources

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