Results 21 to 30 of about 40,026,108 (306)

Viral adaptation to host immune responses occurs in chronic hepatitis B virus (HBV) infection, and adaptation is greatest in HBV e antigen-negative disease [PDF]

, 2012
Hepatitis B virus (HBV)-specific T-cell responses are important in the natural history of HBV infection. The number of known HBV-specific T-cell epitopes is limited, and it is not clear whether viral evolution occurs in chronic HBV infection. We aimed to
Chopra, A., Gordon, A, Scott Bowden, Pfafferott, K, Desmond, P.V., Ian R. James, Revill, P.A., Chopra, A, Mallal, SA, Silvana Gaudieri, Anna Ayres, Lewin, S.R., Thompson, AJ, Desmond, C.P., Jennifer Audsley, James, IR, Locarnini, SA, Stephen A. Locarnini, Sharon R. Lewin, James, I.R., Locarnini, S.A., Chivers, S., Christopher P. Desmond, Desmond, PV, Thompson, A.J., Stuart K. Roberts, Audsley, J, Revill, PA, Lau, GK, Gaudieri, S, Gaudieri, S., Audsley, J., Day, C, Caroline Day, Ayres, A, Day, C., Paul V. Desmond, Pfafferott, K., Gordon, A., Roberts, SK, Peter A. Revill, Alexander J. Thompson, Ayres, A., Desmond, CP, Sarah Chivers, Katja Pfafferott, Bowden, S., George K. Lau, Simon A. Mallal, Lewinb, SR, Lau, G.K., Roberts, S. K., Abha Chopra, Bowden, S, Mallal, S.A., Adam Gordon, Chivers, S   +56 more
core   +1 more source

Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi

BMC Infectious Diseases, 2021
Background The World Health Organization (WHO) has targeted a reduction in viral hepatitis-related mortality by 65% and incidence by 90% by 2030, necessitating enhanced hepatitis B treatment and prevention programmes in low- and middle-income countries ...
Alexander J. Stockdale, Niza M. Silungwe, Isaac Thom Shawa, Benno Kreuels, Melita A. Gordon, Anna Maria Geretti   +5 more
doaj   +1 more source

Anti-hepatitis B virus activity of food nutrients and potential mechanisms of action

Annals of Hepatology, 2023
Hepatitis B virus (HBV) is endemic in many parts of the world and is a significant cause of chronic liver damage and hepatocellular carcinoma. HBV therapeutics vary according to the disease stage.
Alexis Jose-Abrego, Ingrid Rivera-Iñiguez, Luis A. Torres-Reyes, Sonia Roman   +3 more
doaj   +1 more source

Does limited virucidal activity of biocides include duck hepatitis B virucidal action? [PDF]

, 2012
BACKGROUND: There is agreement that the infectivity assay with the duck hepatitis B virus (DHBV) is a suitable surrogate test to validate disinfectants for hepatitis B virucidal activity.
Wutzler, Peter, Bust, Uwe, Peter Wutzler, Michael Schacke, Uwe Bust, Rabenau, Holger, Brigitte Glück, Holger F Rabenau, Glück, Brigitte, Andreas Sauerbrei, Sauerbrei, Andreas, Schacke, Michael   +11 more
core   +2 more sources

Immunological aspects of persistent hepatitis B in children [PDF]

, 2001
We studied the immunological status of 203 children having persistence Hepatitis B (positive HBsAg) ranging in age from 6 to 14 years in Semarang Municipality.
Notoatmojo, Harsoyo
core   +1 more source

Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo

Molecules, 2019
Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang, Jun-Fei Mou, Qin Luo, Qing-Hu Mo, Xian-Li Zhou, Xiao Huang, Qing Xu, Xiang-Duan Tan, Xu Chen, Cheng-Qin Liang   +9 more
doaj   +1 more source

EGF receptor inhibitors comprehensively suppress hepatitis B virus by downregulation of STAT3 phosphorylation

Biochemistry and Biophysics Reports, 2020
Current antiviral therapy can not cure chronic hepatitis B virus (HBV) infection or eliminate the risk of hepatocellular carcinoma. The licensed epidermal growth factor receptor (EGFR) inhibitors have found to inhibit hepatitis C virus replication via ...
Chong J. Gan, Wen F. Li, Chun N. Li, Ling L. Li, Wen Y. Zhou, Xiao M. Peng   +5 more
doaj   +1 more source

HBsAg expression of liver correlates with histological activities and viral replication in chronic hepatitis B

Annals of Hepatology, 2014
Introduction. The intrahepatic hepatitis B surface antigens (HBsAg) expression is related to disease progression of chronic hepatitis B. We examined the features of intrahepatic HBsAg expression.Material and methods.
Pin-Nan Cheng, Yen-Cheng Chiu, Hung-Wen Tsai, Ru-Hsueh Wang, Hung-Chih Chiu, I-Chin Wu, Ting-Tsung Chang   +6 more
doaj   +1 more source

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin, Sanford, Brenton J, Kenney, Scott P, Dryman, Barbara A, Córdoba, Laura, Opriessnig, Tanja   +5 more
core   +1 more source

Correlation Between Quantitative Hepatitis B Surface Antigen and Hepatitis B Virus Deoxyribonucleic Acid Levels in Hepatitis B e Antigen-Positive and Hepatitis B e AntigenNegative Chronic Hepatitis B Patients

Turkish Journal of Gastroenterology, 2020
Background: This study aimed to analyze the relationship between quantitative hepatitis B surface antigen and hepatitis B virus deoxyribonucleic acid in hepatitis B e antigen-positive and hepatitis B e antigen-negative chronic hepatitis B patients and to determine the best cut-off value for quantitative hepatitis B surface antigen to predict high ...
Viva Finhar Insani Nirmala, A. Aryati, Hani Susianti, Syifa Mustika   +3 more
openaire   +3 more sources