Results 21 to 30 of about 70,436 (267)

Chemiluminescent Optical Fiber Immunosensor Combining Surface Modification and Signal Amplification for Ultrasensitive Determination of Hepatitis B Antigen

open access: yesSensors, 2020
Optical fiber based immunosensors are very attractive for biomarker detection. In order to improve the sensor response, we propose a promising strategy which combines porous-layer modification of the fiber surface and streptavidin-biotin-peroxidase nano ...
Xuexue Xu   +3 more
doaj   +1 more source

Are serum quantitative hepatitis b surface antigen levels, liver histopathology and viral loads related in chronic hepatitis b-infected patients?

open access: yesThe Saudi Journal of Gastroenterology, 2016
Background/Aims: Fluctuations in hepatitis B virus (HBV) DNA and alanine transaminase (ALT) levels complicate assessment of the phases of chronic hepatitis B (CHB) infection and correct identification of the inactive HBV carrier state.
Ayhan Balkan   +5 more
doaj   +1 more source

Hepatitis B functional cure and immune response

open access: yesFrontiers in Immunology, 2022
Hepatitis B virus (HBV) is a hepatotropic virus, which damage to hepatocytes is not direct, but through the immune system. HBV specific CD4+ T cells can induce HBV specific B cells and CD8+ T cells.
Jia-Rui Zheng, Zi-Long Wang, Bo Feng
doaj   +1 more source

Seroprevalence of viral hepatitis in riverine communities from the Western Region of the Brazilian Amazon Basin

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
The western region of the Brazilian Amazon Basin has long been shown to be a highly endemic area for hepatitis B and hepatitis D viruses. Data concerning the prevalence of hepatitis C and E viruses in this region are still scarce.
VS de Paula   +3 more
doaj   +1 more source

Diagnostic performance evaluation of hepatitis B e antigen rapid diagnostic tests in Malawi

open access: yesBMC Infectious Diseases, 2021
Background The World Health Organization (WHO) has targeted a reduction in viral hepatitis-related mortality by 65% and incidence by 90% by 2030, necessitating enhanced hepatitis B treatment and prevention programmes in low- and middle-income countries ...
Alexander J. Stockdale   +5 more
doaj   +1 more source

Anti-hepatitis B virus activity of food nutrients and potential mechanisms of action

open access: yesAnnals of Hepatology, 2023
Hepatitis B virus (HBV) is endemic in many parts of the world and is a significant cause of chronic liver damage and hepatocellular carcinoma. HBV therapeutics vary according to the disease stage.
Alexis Jose-Abrego   +3 more
doaj   +1 more source

Monoclonal Antibodies Specific for Hepatitis B e Antigen and Hepatitis B Core Antigen

open access: yesHybridoma, 2011
Despite effective vaccination programs in many countries, HBV infection is still a serious health problem throughout the world; more than 2 billion people have been infected with Hepatitis B virus (HBV). The serologic markers are crucial indicators in clinical diagnosis of HBV infection. The persistent presence of anti-HBc is associated with chronicity,
Sogut, Ibrahim   +3 more
openaire   +3 more sources

Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo

open access: yesMolecules, 2019
Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang   +9 more
doaj   +1 more source

EGF receptor inhibitors comprehensively suppress hepatitis B virus by downregulation of STAT3 phosphorylation

open access: yesBiochemistry and Biophysics Reports, 2020
Current antiviral therapy can not cure chronic hepatitis B virus (HBV) infection or eliminate the risk of hepatocellular carcinoma. The licensed epidermal growth factor receptor (EGFR) inhibitors have found to inhibit hepatitis C virus replication via ...
Chong J. Gan   +5 more
doaj   +1 more source

HBsAg expression of liver correlates with histological activities and viral replication in chronic hepatitis B

open access: yesAnnals of Hepatology, 2014
Introduction. The intrahepatic hepatitis B surface antigens (HBsAg) expression is related to disease progression of chronic hepatitis B. We examined the features of intrahepatic HBsAg expression.Material and methods.
Pin-Nan Cheng   +6 more
doaj   +1 more source

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