Results 101 to 110 of about 1,357,812 (346)

Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow, Nicola McKern, Vincent Oxenham, Kate Ahmad, Omar Ahmad   +4 more
wiley   +1 more source

Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]

, 2009
The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa, James Spencer, Janice D. Thomas, Jeffrey H. Toney, Joseph G. Moloughney, Karla S. Bullon   +5 more
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

The functional antagonist of sphingosine-1-phosphate, FTY720, impairs gut barrier function

Frontiers in Pharmacology
FTY720 or fingolimod is a known functional antagonist of sphingosine-1-phosphate (S1P), and it is effective in treating multiple sclerosis and preventing inflammatory bowel disease (IBD).
Sohini Sikdar, Debmalya Mitra, Oishika Das, Moumita Bhaumik, Shanta Dutta   +4 more
doaj   +1 more source

Antimicrobial resistance in Enterobacteriaceae from healthy broilers in Egypt: emergence of colistin-resistant and extended-spectrum β-lactamase-producing Escherichia coli

Gut Pathogens, 2018
Background Poultry remains one of the most important reservoir for zoonotic multidrug resistant pathogens. The global rise of antimicrobial resistance in Gram-negative bacteria is of reasonable concern and demands intensified surveillance.
Amira A. Moawad, Helmut Hotzel, Heinrich Neubauer, Ralf Ehricht, Stefan Monecke, Herbert Tomaso, Hafez M. Hafez, Uwe Roesler, Hosny El-Adawy   +8 more
doaj   +1 more source

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core  

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Delving into the genome of resurged Shigella dysenteriae Type 1

One Health Outlook
Background The Gram-negative enteric bacterium Shigella dysenteriae serotype 1 (Sd1) has historically caused several dysentery epidemics but has largely disappeared from the global epidemiological landscape, with the last reported isolate dating back to ...
Agila Kumari Pragasam, Goutam Chowdhury, Madhuchhanda Das, Rachana Khati, Asish K. Mukhopadhyay, Samaresh Das, Shanta Dutta, Karma Gurmey Dolma, Thandavarayan Ramamurthy   +8 more
doaj   +1 more source

Assessing Infection Patterns, Resistant Pathogens and Targeted Bacterial Mechanisms: A Comparative Analysis of Antimicrobial Resistance in Five Countries

, 2023
Ayesha Ayesha, Saba Shafi, Noor Fatima, Muhammad Ali, Shah Zeb, Irum Basheer   +5 more
openalex   +1 more source

Unlocking the Power of Quercetin‐Encapsulated Mesoporous Bioactive Glass Nanoparticles: A Multifunctional Approach to Bone Regeneration

Advanced Engineering Materials, EarlyView.
Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello, Qaisar Nawaz, Pier Francesco Ferrari, Laura Pastorino, Roberto Raiteri, Aldo R. Boccaccini   +5 more
wiley   +1 more source