Results 181 to 190 of about 861,479 (259)

Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections with Polymyxins: A Review. [PDF]

Infect Drug Resist
Li X, Chong W, Mo J, Liu J.
europepmc   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Microbial-Responsive Wound Dressings Based on Biopolymer Degradation Strategy for Detecting Bacterial Infections. [PDF]

ACS Appl Mater Interfaces
Sadati S, Swann MJ, Percival SL, Charmet J, Unnikrishnan M, Isakov D.   +5 more
europepmc   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Risk Factors, Pathogen Distribution, and Treatment Strategies for Mortality in Elderly Patients with Pulmonary Bacterial Infections. [PDF]

Clin Interv Aging
Chen Z, Bai N, Chi Y, Liang B, Cai Y.
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Antibody-Antibiotic Conjugates: Mechanisms, Clinical Progress, and Next-Generation Strategies Against Multidrug-Resistant Bacterial Infections. [PDF]

Microbiologyopen
Askari P, Eshaghi S, Omidvar L, Mahi-Birjand M.   +3 more
europepmc   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Clinical Characteristics and Early Evolution of Neonates with Perinatal Gram-Negative Bacterial Infections. [PDF]

Children (Basel)
Zaharie M, Manea AM, Boia M, Costescu O, Cioboata D, Brandibur T, Iacob D.   +6 more
europepmc   +1 more source