Results 1 to 10 of about 108,343 (213)

The public health utility of whole genome sequencing: Insights from a tuberculosis outbreak in Australia and perspectives of public health professionals. [PDF]

PLOS Global Public Health
Whole Genome Sequencing (WGS) is increasingly being used to enhance tuberculosis (TB) surveillance and management. However, evidence on how WGS shapes real-world decision-making remains limited.
Daisy Wang, Angeline Ferdinand, Justin T Denholm, Katie Dale, Simone Bittmann, Maria Globan, Ben J Marais, Vitali Sintchenko, Christopher Coulter, Martyn D Kirk   +9 more
doaj   +2 more sources

WGS sequencing

, 2011
The Shanghai Institutes for Biological Sciences (SIBS), China in collaboration with BGI-SZ (China) is sequencing the Metarhizium acridum (aka Metarhizium anisopliae var. acridum) strain CQMa 102 genome at 113x coverage using whole genome shotgun (WGS) sequencing.
DOE Joint Genome Institute (17854997)
openaire   +2 more sources

Sanger validation of WGS variants

Scientific Reports
With the development of next-generation sequencing (NGS) technologies it became possible to simultaneously analyze millions of variants. Despite the quality improvement, it is generally still required to confirm the variants before reporting. However, in
Arina Kopernik, Mariia Sayganova, Gaukhar Zobkova, Natalia Doroschuk, Anna Smirnova, Daria Molodtsova-Zolotukhina, Olesya Sagaydak, Oxana Ryzhkova, Sergey Kutsev, Olga Groznova, Lyusya Melikyan, Elizaveta Bondarchuk, Mary Woroncow, Eugene Albert, Viktor Bogdanov, Pavel Volchkov   +15 more
doaj   +3 more sources

Healthcare workers’ perceptions of the potential value of whole-genome sequencing for post-exposure management of rifampicin-resistant tuberculosis: a qualitative study [PDF]

BMC Health Services Research
Background Rifampicin-resistant tuberculosis (RR-TB) remains a public health challenge, with suboptimal treatment outcomes and challenging management of contacts.
Caitlin D. October, Busisiwe Beko, Anja Reuter, Vincent Rennie, Nabila Ismail, Emilyn Costa Conceição, Susanne Tonsing, Rob Warren, Stephanus Malherbe, Annelies Van Rie, Lario Viljoen   +10 more
doaj   +2 more sources

Single whole genome sequencing analysis blazes the trail for precision medicine

Cancer Biology & Therapy, 2022
As precision oncology evolves toward developing more targeted therapies, sequencing has moved to the forefront of treatment decision-making. Whole genome sequencing (WGS) has emerged as a technology capable of identifying candidates for rare and targeted
Giulia C. Napoli, Cindy H. Chau, William D. Figg   +2 more
doaj   +1 more source

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
doaj   +1 more source

Mink SARS-CoV-2 infection in Poland – short communication

Journal of Veterinary Research, 2021
Since April 2020, when the first SARS-CoV-2 infection was reported in mink and subsequently in mink farm workers in the Netherlands, it has been confirmed that human-to-mink and mink-to-human transmission can occur.
Domańska-Blicharz Katarzyna, Orłowska Anna, Smreczak Marcin, Niemczuk Krzysztof, Iwan Ewelina, Bomba Arkadiusz, Lisowska Anna, Opolska Justyna, Trębas Paweł, Potyrało Patrycja, Kawiak-Sadurska Magdalena, Rola Jerzy   +11 more
doaj   +1 more source

Palmer Lab High Coverage WGS DeepVariant Genotyping Pipeline

, 2023
<p>The very first version of Palmer Lab's High Coverage WGS DeepVariant Genotyping Pipeline v1.0.0. Acceptable sequencing data: High Coverage WGS</p>If you use this pipeline or use data generated by this pipeline, please cite it as ...
Chitre, Apurva, Cheng, Riyan, Palmer, Abraham, Polesskaya, Oksana, Chen, Denghui, Peng, Beverly   +5 more
core   +1 more source

WG-Alltag

Göttinger Rechtszeitschrift, 2023
Der Fall wurde im WS 2022/23 in der Fortgeschrittenenübung im Strafrecht an der Georg-August-Universität Göttingen gestellt. Im Kern geht es um die Konstellation des kontaktlosen Bezahlens mit fremder EC-Karte, die noch nicht abschließend geklärt ist. Die Bearbeiter:innen mussten demgemäß mit Delikten, die als gesteigert schwierig empfunden werden, und
Peter Rackow, Emilia Wehlitz
openaire   +1 more source

Clinical sequencing: is WGS the better WES? [PDF]

, 2016
Current clinical next-generation sequencing is done by using gene panels and exome analysis, both of which involve selective capturing of target regions. However, capturing has limitations in sufficiently covering coding exons, especially GC-rich regions.
Oexle, Konrad, Konrad Oexle, Matyas, Gabor, Rémy Bruggmann, Gabor Matyas, Bruggmann, Rémy, Meienberg, Janine, Janine Meienberg, Matyas G, Meienberg J, Oexle K, Bruggmann R   +11 more
core   +3 more sources