Results 41 to 50 of about 98,982 (312)
IJTLD OpenBACKGROUND: Multidrug- and extensively drug-resistant strains of Mycobacterium tuberculosis complex (MTBC) remain a significant global health challenge.
A. Ghodousi +6 more
doaj +1 more source
Resynchronization Attacks on WG and LEX [PDF]
, 2006 WG and LEX are two stream ciphers submitted to eStream – the ECRYPT stream cipher project. In this paper, we point out security flaws in the resynchronization of these two ciphers. The resynchronization of WG is vulnerable to a differential attack. For WG with 80-bit key and 80-bit IV, 48 bits of the secret key can be recovered with about 231.3 chosen ...
Hongjun Wu 0001, Bart Preneel
openaire +2 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
transcribing-WGS: Working release
, 2015 <p>This code powered the application for transcription of the Worthington George Smith archive.</p ...
Daniel Pett
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Microorganisms, 2019 Human infections with Brucella melitensis are occasionally reported in Sweden, despite the fact that the national flocks of sheep and goats are officially free from brucellosis. The aim of our study was to analyze 103 isolates of B.
Lorena Sacchini +6 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
IJTLD OpenBACKGROUND: Molecular typing of Mycobacterium tuberculosis isolates provides insight into TB transmission by identifying clustering isolates. However, clustering alone does not necessarily indicate ongoing in-country transmission, as infections may have ...
W. Frederiks, R.M. Anthony, G. de Vries
doaj +1 more source
Nuclear Physics News, 2017 The International Union of Pure and Applied Physics (IUPAP) established a working group for nuclear physics—Working Group 9 (WG.9)—during its general assembly meeting in 2005. The working group was an out-growth of an IUPAP Commission C12 committee that focused on nuclear physics facilities.
Tribble, Bob, Van Oers, Wim
openaire +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source