Results 251 to 260 of about 2,424,208 (316)

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Targeting cGAS-STING signaling to overcome antibiotic-resistant bacterial infections: Challenges and opportunities. [PDF]

Sci Adv
Ham YS, Jeong M, Yang CS.
europepmc   +1 more source

Femtosecond‐Laser Nanocavitation Regenerates SERS‐Active Plasmonic Nanogaps for Longitudinal Molecular Sensing at Biointerfaces

Advanced Science, EarlyView.
A regenerative molecular sensing platform that co‐localizes surface‐enhanced Raman spectroscopy (SERS) sensing and nanocavitation‐based actuation. Femtosecond‐laser triggered nanocavitation produces thermomechanical forces to locally regenerate SERS‐active nanogaps in protein‐rich biofluids while preserving optical performance.
Aditya Garg, Ze Zong, Meitong Nie, Stacie E. Deaver, Elizabeth M. Van Order, Elieser Mejia, Peter Vikesland, Erin S. Gloag, Wei Zhou   +8 more
wiley   +1 more source

Detection Blind Spots in Microbial Culture, tNGS, and mNGS: Anaerobic Bacterial Infections in the Lung-A Retrospective Analysis of Two Cases. [PDF]

Infect Drug Resist
Zhuang J, Yu Z, Jin C, Qiu H, Wu Y, Feng Q, Zheng S, Wang J.   +7 more
europepmc   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

Advanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang, Weijing Han, Jing Shi, Lisha Wang, Cuijuan Teng, Wei Lin, Jun Fan, Shuang Wang   +7 more
wiley   +1 more source

Urease Inhibitors from <i>Nasturtium officinale</i> Extract for the Treatment of Urease Expressing Bacterial Infections. [PDF]

ACS Pharmacol Transl Sci
Heylen R, Owen E, Stewart K, Winyard PG, Jenkins ATA.   +4 more
europepmc   +1 more source

Engineering Human Donor Derived Germinal Center‐Like Organoids (GCLOs) for Studying Immune Response to Vaccination

Advanced Science, EarlyView.
We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar, Carlos Gomez, Giancarlo Asencio, Suresh Pallikkuth, Ashutosh Agarwal   +4 more
wiley   +1 more source

Eravacycline as a Novel Option for Treating Multidrug-Resistant Gram-Negative and Gram-Positive Bacterial Infections: A Narrative Review. [PDF]

J Clin Med
Złotowska A, Kacer J, Dybko Z, Dudek M, Duszyńska W.   +4 more
europepmc   +1 more source

Analysis of risk factors for multidrug-resistant bacterial infections in intensive care units and application of a nomogram prediction model. [PDF]

Medicine (Baltimore)
Fu Y, Zhao XR, Luo JJ, Li F, Zhang ZH, Li RY, Liu YX.   +6 more
europepmc   +1 more source

Diagnostic performance of eosinopenia for identifying bacterial infections in the emergency department: a prospective multicenter study. [PDF]

BMC Emerg Med
Lavoignet CE, Bilbault P, Lefebvre F, De Carlo V, Bejinariu L, Chevrolet-Lavoignet J, Schweitzer F, Zayet S, Dussert P, Abensur Vuillaume L, Le Borgne P.   +10 more
europepmc   +1 more source