Results 31 to 40 of about 2,339,393 (260)

Indoor Bacterial Exposure in Sick Buildings and Associated Inflammatory Pathways in Humans: A Mini-Review [PDF]

open access: yesJournal of Advances in Environmental Health Research
Indoor air quality (IAQ) and sick building syndrome (SBS) have long been public health concerns, which were further exacerbated by the COVID-19 pandemic.
Mahsa Hajivalili   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Brain effects of gestating germ-free persist in mouse neonates despite acquisition of a microbiota at birth

open access: yesFrontiers in Neuroscience, 2023
At birth, mammals experience a massive colonization by microorganisms. We previously reported that newborn mice gestated and born germ-free (GF) have increased microglial labeling and alterations in developmental neuronal cell death in the hippocampus ...
Alexandra Castillo-Ruiz   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Cotton and Surgical Face Masks in Community Settings: Bacterial Contamination and Face Mask Hygiene

open access: yesFrontiers in Medicine, 2021
During the current COVID-19 pandemic, the use of face masks has become increasingly recommended and even mandatory in community settings. To evaluate the risk of bacterial cross-contamination, this study analyzed the bacterial bioburden of disposable ...
Lize Delanghe   +9 more
doaj   +1 more source

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis [PDF]

open access: yes, 2019
Rationale: The principal underlying inhaled antibiotic treatment in bronchiectasis is that airway bacterial load drives inflammation, and therefore antibiotic treatment will reduce symptoms.Objectives: To determine the relationship between bacterial load
Laserna, Elena   +10 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Proximate Composition, Retained Water, and Bacterial Load for Two Sizes of Hybrid Catfish (Ictalurus furcatus × Ictalurus punctatus) Fillets at Different Process Steps

open access: yesFoods, 2023
The catfish processors in the US are required to state the maximum percentage of retained water content (RWC) on the product label. The objectives of our study were to quantify the RWC of processed hybrid catfish fillets from proximate composition and ...
Manirul Haque, Juan L. Silva
doaj   +1 more source

Bacterial Load Assessment of some Food Items Sold in Street in Woldia Town, North-East Ethiopia

open access: yes, 2020
Infectious diseases due to contaminated street vended food items has happened to an essential concern and public health issue in low socio-economic status individuals. The goal of this study was to evaluate bacterial quality and safety of some food items
Kindu Alem
core   +1 more source

Home - About - Disclaimer - Privacy