Results 41 to 50 of about 2,339,393 (260)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Feasibility of Miscanthus as alternative bedding for dairy cows
Despite dairy farmers' awareness of the importance of correct bedding for the health and comfort of their cows, they are often frugal with respect to these bedding materials in order to reduce costs.
S. Van Weyenberg +5 more
doaj +1 more source
Human Rhinovirus at Naturally Occurring COPD Exacerbation [PDF]
Chronic obstructive pulmonary disease (COPD) is an inflammatory condition of the lung caused by an abnormal response to particles and noxious gases, primarily cigarette smoke.
George, SN
core
Background: A common challenge of nail avulsion surgery is the associated bacterial contamination and infection that can manifest. The toe has a difficult anatomy to antiseptically prepare and properly maintain throughout the surgical procedure, lending ...
Luis Alou Cervera +9 more
core +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Microbial Quality and Mineral Content of Water Consumed in Ho Municipality of Volta Region, Ghana [PDF]
Background: Water quality and safety are fundamental to human development and well-being. Therefore, the purpose of this study was to determine the bacteriological and mineral content of water in Ho, the capital city of the Volta Region of Ghana ...
G. Aboagye, P.G. Akpaloo, T.A. Avle
doaj
Objectives: Pulmonary tuberculosis (PTB) is a leading infectious disease and a major public health concern. Out of susceptible genes, nuclear factor kappa B (NF-κB) gene influences inflammation and hence the progression of the disease.
Pallavi Baliarsingh +4 more
doaj +1 more source
Mating history bacterial load data (follow-up experiment)
Mating history bacterial load data (follow-up ...
Balasubramaniam, Thiropa +9 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

