Results 61 to 70 of about 2,339,393 (260)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Frontiers in Immunology, 2019 Background: Prior Influenza A viral (IAV) infection has been shown to increase susceptibility to tuberculosis (TB) and TB has also been shown to be a primary cause of death during pandemics, including the Spanish Influenza outbreak of 1918–1919.
Joseph Mendy +6 more
doaj +1 more source
Characteristics and treatment of the 64 high bacterial load (HBL) patients.
, 2021 Characteristics and treatment of the 64 high bacterial load (HBL) patients.
Bouke Catherine de Jong (4557247) +13 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyIntroductionColorectal cancer is one of the most common malignancies worldwide, and microbiome research has strong potential to advance understanding of tumor biology and to support biomarker development and microbiome-targeted interventions.
Nikolay K. Shakhpazyan +8 more
doaj +1 more source
Irish Veterinary Journal, 2021 Background Teat disinfection is an important step in the control of mastitis within a dairy herd. The objective of this study was to evaluate the effectiveness of 96 commercially available teat disinfectant products in Ireland against bacterial isolates ...
Sarah Rose Fitzpatrick +4 more
doaj +1 more source
Stool bacterial load in preterm infants with necrotising enterocolitis [PDF]
, 2016 Resected gut tissue in necrotising enterocolitis (NEC) has a higher bacterial load than controls. Quantitative PCR was performed on longitudinal NEC and control stool samples (n = 72).
Abdulkadir, Bashir +11 more
core +1 more source
Bacterial load in tissues of A. baumannii ACC001 infected mice.
, 2021 Bacterial load in tissues of A. baumannii ACC001 infected mice.
Maria Elisa Perico (11784765) +7 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source