Results 61 to 70 of about 199,924 (308)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reduction in bacterial load using hypochlorous acid hygiene solution on ocular skin [PDF]

, 2017
David W Stroman,1 Keri Mintun,1 Arthur B Epstein,2 Crystal M Brimer,3 Chirag R Patel,4 James D Branch,5 Kathryn Najafi-Tagol1 1NovaBay Pharmaceuticals, Inc., Emeryville, CA, 2Ophthalmic Research Consultants of Arizona, Phoenix, AZ, 3Crystal Vision ...
Mintun K, Stroman DW, Brimer CM, Branch JD, Patel CR, Epstein AB, Najafi-Tagol K   +6 more
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Nonequivalence of membrane voltage and ion-gradient as driving forces for the bacterial flagellar motor at low load [PDF]

, 2007
Many bacterial species swim using. agella. The. flagellar motor couples ion. ow across the cytoplasmic membrane to rotation. Ion flow is driven by both a membrane potential (Vm) and a transmembrane concentration gradient. To investigate their relation to
Richard M. Berry, Berry, RM, Teuta Pilizota, Leake, Mark C., Pilizota, T, Berry, Richard, Chien-jung Lo, Leake, MC, Lo, Chien-Jung, Pilizota, Teuta, Mark C. Leake, Berry, Richard M., Lo, CJ, Leake, Mark   +13 more
core   +1 more source

Feasibility of Miscanthus as alternative bedding for dairy cows

Veterinární Medicína, 2015
Despite dairy farmers' awareness of the importance of correct bedding for the health and comfort of their cows, they are often frugal with respect to these bedding materials in order to reduce costs.
S. Van Weyenberg, T. Ulens, K. De Reu, I. Zwertvaegher, P. Demeyer, L. Pluym   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Gonococcal bacterial load in PrEP users with Mycoplasma genitalium coinfection [PDF]

, 2021
: Objectives Gonococcal infections with a higher bacterial load may pose a higher risk of transmission. We assessed the association between gonococcal bacterial load and coinfection with Mycoplasma genitalium.
Cuylaerts, Vicky, Laumen, Jolein, Vuylsteke, Bea, Van Dijck, Christophe, Buyze, Jozefien, De Baetselier, Irith, Kenyon, Chris   +6 more
core  

Study on association of nuclear factor kappa B gene polymorphism with bacterial load in pulmonary tuberculosis

The Journal of Association of Chest Physicians, 2023
Objectives: Pulmonary tuberculosis (PTB) is a leading infectious disease and a major public health concern. Out of susceptible genes, nuclear factor kappa B (NF-κB) gene influences inflammation and hence the progression of the disease.
Pallavi Baliarsingh, Pratima Kumari Sahu, Paresh Nath Mohanty, Roma Rattan, Monalisa Mohapatro   +4 more
doaj   +1 more source

Bacterial and Fungal Load of termites

, 2020
Termites are cellulose eating social insects belonging to the other Isoptera. The microbial load of termites collected from residential premises in Ekpoma and Jos in a traditional method was carried out using serial dilution method of the homogenates.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source