Results 171 to 180 of about 150,001 (350)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Childhood bacterial meningitis in Bulgaria: a population-based retrospective study in six regions during 1992–1996

open access: gold, 2003
Mira Kojouharova   +4 more
openalex   +1 more source

Fatal Outcome due to Disseminated Cryptococcosis in a Patient With HIVrequiring Veno‐Arterial Extracorporeal Membrane Oxygenation: A Case Report

open access: yesAcute Medicine &Surgery, Volume 13, Issue 1, January/December 2026.
This report details a fatal case of fulminant disseminated cryptococcosis in a young male with undiagnosed HIV. He rapidly developed multi‐organ failure, refractory shock, and cardiac arrest. Autopsy revealed extensive myocardial cryptococcal infiltration and microemboli, suggesting a critical role in the acute refractory shock that led to his death ...
Taisei Sasamoto   +3 more
wiley   +1 more source

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh   +5 more
wiley   +1 more source

Sigmoid and Transverse Sinus Thrombosis as a Complication of Chronic Suppurative Otitis Media in a Child: A Case Report and Review of Literature

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Chronic suppurative otitis media is an easily managed condition with potential for severe sinus thrombophlebitis complications secondary to cholesteatoma, if not diagnosed and treated promptly. Diagnosis relies on the culture and sensitivity of the drained suppuration, computed tomography (CT), and magnetic resonance imaging (MRI).
Abdullah Nadeem   +8 more
wiley   +1 more source

A Twist in the Tale: The Unmasking of Listeria in a PMR Case

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT In general, an older patient presenting with proximal muscle pain and fatigue, with elevated inflammatory markers, would generally result in an extensive evaluation. If this is negative, it would be reasonable for a diagnosis of polymyalgia rheumatica (PMR) to be made and the patient referred to rheumatology.
Ghassan Al‐Qaysi   +3 more
wiley   +1 more source

Cerebrospinal fluid cytokines in the diagnosis of bacterial meningitis in infants [PDF]

open access: bronze, 2016
Lakshmi Srinivasan   +4 more
openalex   +1 more source

Cerebral Abscess Masquerading as Tuberculoma in a Post‐Renal Transplant Chronic Kidney Disease Patient: A Diagnostic and Therapeutic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Solid organ transplant recipients are at increased risk of acquiring serious infections. We present a case of a 48‐year‐old male with a history of renal transplantation in 2012, chronic kidney disease (CKD) Stage 4, hypertension, uncontrolled diabetes mellitus, and prior tuberculous pleural effusion.
Sakib Abrar   +3 more
wiley   +1 more source

A Rare Clinical Manifestation of Disseminated Tuberculosis: Case Report of Tuberculous Meningitis With Flaccid Paralysis

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This case highlights a rare presentation of disseminated tuberculosis in a child, manifesting as tuberculous meningitis and flaccid paralysis due to spinal tuberculosis. Timely initiation of antitubercular therapy, corticosteroids, and ventriculoperitoneal shunt placement led to full recovery, emphasizing tuberculosis consideration in atypical
Aisha Haleem   +5 more
wiley   +1 more source

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